A better understanding of neural activity and the development of cortical connections and networks is an important requirement for evaluating the cause and treatment of neonatal seizures. There have been many advances in the management of neonatal seizures such as increased use of EEGs, therapeutic hypothermia for HIE and exome sequencing, to name a few. Neonatal Seizures, Current Management, Future Challenges distils what is known about these advances into one scholarly yet practical text.

Now In Its Third Edition, Breastfeeding Management For The Clinician: Using The Evidence Is A Trusted Compendium On Breastfeeding For The Practicing Clinician. It Provides A Research-Based Approach To Breastfeeding Care By Including Literature Reviews While Covering The Incidence, Etiology, Risk Factors, Prevention, Prognosis And Implications, Interventions, Expected Outcomes, Care Plans, And Clinical Algorithms. Expanded To Include New Approaches To Solving Common And Uncommon Breastfeeding Problems, The Third Edition Discusses The Political And Social Landscape Of Breastfeeding Including New State And Federal Laws And Policies Related To Breastfeeding. Also Explained And Clarified Are New Revelations About Infant Sucking Mechanics As Seen Under Ultrasound Presented As A Combination Of Vacuum And Compression. Breastfeeding Management For The Clinician: Using The Evidence, Third Edition Provides Both The Problem Solving Approach Busy Clinicians Need To Resolve Issues Encountered In Everyday Practice And The Evidence-Based Foundation They Need To Impact Positive Change In The Workplace.

In this book, the authors present new research in the study of neonatal care. Topics discussed include the effects of maternal stress and intrauterine environmental factors on foetal behaviour and central brain processes related to cognition, memory and habituation; phosphodieterases and their inhibitors in some respiratory system disorders; glucocorticoids in meconium aspiration syndrome and the possible benefits versus the risks of treatment; and the evidence linking hyperbilirubinemia to auditory neuropathy and prelingual deafness.

Paediatric orthopaedics deals with the diagnosis and management of diseases and injuries in bones, joints, muscles and nerves, in children. The second edition of Neonatal Orthopaedics examines orthopaedics problems in neonates, focussing on antenatal diagnostic measures, diagnostic points and salient features of each disorder. The book begins with an introduction to the general aspects of neonatal orthopaedics, discussing anatomy and physiology, antenatal diagnosis, genetics, skeletal and muscular disorders and birth injuries. The following sections describe various disorders found in different parts of the neonate body - lower limb, vertebral, upper limb and shoulder. Each chapter discusses in detail conditions that may be encountered, describing their etiology, clinical features, differential diagnosis and treatment. Keywords for each chapter have also been included. The final sections discuss neonatal infections and miscellaneous conditions including tetanus, gangrene, conjoined twins and rheumatic disorders. Key points Second edition examining etiology, clinical features, diagnosis and treatment of orthopaedics disorders in neonates Features diseases and injuries in all sections of the body Each chapter includes a keywords' box Previous edition published in 2007

Meconium aspiration syndrome (MAS) is a major cause of respiratory morbidity and mortality in the term and post-term new-borns. Aspirated meconium obstructs the airways and subsequently may cause an alveolar atelectasis behind the plug, air-trapping, and air leak. In a very short time after the aspiration, meconium triggers a progressive dysfunction of pulmonary surfactant, chemical pneumonia, and ventilation/perfusion mismatch, which often leads to persistent pulmonary hypertension. Due to complex pathophysiology and multiple interactions between the individual pathomechanisms, MAS is often difficult to treat. Therapeutic protocols usually include airway suctioning, ventilator support or artificial ventilation, in severe cases also administration of exogenous surfactant, inhaled NO, partial liquid ventilation, or anti-inflammatory treatment. Growing information on the role of various pathomechanisms participating in the meconium-induced respiratory, inflammatory, and cardiovascular changes widens the spectrum of drugs which may be perspectively beneficial in the treatment of MAS.

The objective of this book is to review specific haematologic disorders that commonly present in the new-born period. It summarises and presents the topics specifically relating to the haematological disorders in neonates.

Birth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth. These abnormalities lead to mental or physical disabilities or are fatal. There are more than 4,000 different known birth defects ranging from minor to serious, and although many of them can be treated or cured, they are the leading cause of death in the first year of life. This book presents leading research in this field from around the world.

Birth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth. These abnormalities lead to mental or physical disabilities or are fatal. There are more than 4,000 different known birth defects ranging from minor to serious, and although many of them can be treated or cured, they are the leading cause of death in the first year of life. This book presents leading research in this field from around the world.

There is a rapidly growing international literature on very early infant relationships. Many authors have addressed the psychological aspects of neonatal intensive care and indicated a need for greater understanding and research into the links between caregiving interventions and the baby's physical and emotional development. This book looks specifically at the experiences of the premature baby in hospital and how the way professionals and parents interact with it and between themselves affects its future development. The author draws from psychoanalysis, developmental psychology, and ethnology, but takes a systemic perspective throughout. Observational material graphically illustrates the theoretical points and makes the book particularly useful for the practitioner and student.

Human Placental Trophoblasts: Impact of Maternal Nutrition explores the vital roles of trophoblasts play in fetal growth and pregnancy, giving you new insight into the modulation of placental trophoblast functions by nutrients. It also reviews the role of fatty acids, folic acids, and specific vitamins in this aspect. The book highlights the critical role of nutrients on human placental development and its' in utero programming effects on the development of chronic diseases such as type 2 diabetes, cardiovascular diseases, hypertension, and obesity in later life. The book begins with discussions of the central process of placentation and its regulation on size and growth of the fetus. It also covers the effects of key macronutrients on placental growth, metabolism, transport, and secretory function. The text details important vitamins and few micronutrients and their roles in the feto-placental growth and development. It includes information on the influence of maternal lifestyle and environmental factors on regulation of the growth, metabolism and gene expression in the feto-placental unit. A review of the genes linked to the process of placentation rounds out the coverage. An examination of a broad range of evidence in the areas of placental growth, function, and its impact on feto-placental outcome, the book presents new knowledge on nutrition and its relevance with early human development. This includes not only the effects of maternal nutrients on possible neonatal growth and development but also their regulation by maternal lifestyle associated factors. A fine blending of epidemiology, clinical nutrition, perinatal and neonatal medicine, and biochemistry and molecular biology areas of research activities, the book helps you to understand the impact of maternal nutrition on placentation and its relevance with pregnancy outcome and fetal programming of adult health and disease.

Neonatal intensive care unit (NICU) teams in the US and around the world receive performance reports that locate their particular value for selected process and outcome measures within the range of values from all reporting NICUs. Understandably, many providers focus primarily, if not exclusively, on their particular value. When a value appears undesirable, providers often justify it in an apparent reflex response rather than critically analysing their data. Exceedingly few reflect on the width or implications of the range within which their performance lies. Standard medical education does not include these skills, yet unwarranted practice variation necessarily compromises a population's overall quality of care. Researchers report wide variation in health care resource use with little connection to patient outcomes, challenging the belief that directing incrementally more resources at certain healthcare problems necessarily produces better results. This book provides requisite knowledge to enable readers without research expertise to understand the notion of unwarranted practice variation, how to recognize it, its ubiquity, and why it is generally undesirable - why narrowing is pervasiveness improves quality. The book begins by describing practice variation, its prevalence, and why it matters. Next, it examines alternative conceptualizations of NICU work. One view is task-oriented, while the other is aim-oriented. NICU teams rarely articulate their aims explicitly, so this book offers examples that guide thinking and action. Finally, this book asks, "Which rate is 'right'; what is the performance target?" The answer entails identifying the lowest resource use rate associated with desirable outcomes. This requires data describing efficient and predictably performing provision of current evidence-based care, along with relationships to a variety of outcomes. Provider conceptualization of healthcare quality also is often vague. The challenge lies in defining this notion operationally. This book does precisely that and gives readers tools to think critically about process, outcome, and quality measures, via some understanding of systems, risk-adjustment modelling, and discriminating signal from noise in process data.

This comprehensive, up-to-date reference on surgery in the neonate presents and explains the latest developments in the diagnosis and treatment of neonatal malformations and surgical pathologies. The coverage includes conditions involving the head and neck and the chest, disorders of the liver and biliary tract, gastrointestinal disorders, genitourinary conditions and malformations, anterior abdominal wall defects, tumors, and various other pathologies. For each condition, the pathogenesis and the most current and innovative surgical, and also medical, approaches are described with the aid of numerous illustrations. Minimally invasive strategies receive particular attention, and tips and tricks that will be of value in clinical practice are highlighted. The book includes a general part covering topics such as embryology, anatomy, prenatal diagnosis, and anesthesia and also provides detailed advice on pre- and postoperative care, with special consideration of nutritional problems. Neonatal Surgery will serve as an excellent guide for all pediatric and neonatal surgeons, whether in training or experienced

Cancer in pregnancy presents physicians with a serious and ethical challenge, yet the sources of concise data and guidance for the management of this disease are scarce. The Motherisk program, based at the Hospital for Sick Children, Toronto, is dedicated to addressing this problem. Cancer in Pregnancy and Lactation: The Motherisk Guide tackles this subject by providing evidence-based information needed to address the complex issues of maternal diagnosis, management, treatment, prognosis and long-term impact on the unborn child. Based on the research by members of the international Consortium of Cancer in Pregnancy Evidence (CCoPE) this book provides physicians with the core knowledge required to make sound clinical decisions in the face of sometimes conflicting interests. Co-edited by recognized experts in the field with over 25 years' experience, this comprehensive volume is essential reading for all maternal-fetal medicine physicians, obstetricians, neonatologists, oncologists and pharmacologists.

Doctors, midwives and other professionals entering the field of postnatal care frequently feel ill-prepared for the task, and a lack of accessible and relevant learning resources can leave learning on the job as the only realistic option. This combined book and DVD resource has been specifically created to provide an accessible guide to the clinical problems those new to postnatal care will face: what to do, how to counsel parents, and how to manage the most common scenarios. Demystifying the transition into the field, it provides practical solutions, and access to relevant background information through extensive references. The accompanying DVD explores specific areas though audiovisual presentations, including jaundice, hypoglycaemia, common issues in newborn examinations and neonatal management of antenatally-detected renal tract dilation. Created by experienced consultant neonatologists and senior trainees who deal regularly with the recurrent themes of day-to-day newborn care, this groundbreaking resource will be essential reading and viewing for all doctors, midwives, nurses and other health professionals new to the field.

This book critically analyzes the place of caesarean in childbearing at the beginning of the twenty first century. It questions the changes that are taking place in childbirth and, in particular, the effects and implications of an increase in caesarean births.

This controversial work by a practising midwife and researcher, includes discussion of:

• the context of the operation and description of it
• health systems around the world and their caesarean incidence rates
• decision-making and cultural/medical constraints
• the short and long term implications of caesarean for baby and mother.

Using up-to-date research, Rosemary Mander bases her argument on a firm evidence-base and argues that the rapidly rising caesarean section rate may not be for the benefit of either the woman giving birth or her baby. Rather, the beneficiaries may actually be those professionals whose investment is in extending the range of theirinfluence and thus increasing the medicalization of normal life.

Extreme Prematurity examines the controversial issues surrounding the clinical management of this group of neonates by the intervention of modern neonatal intensive care. The foregoing of life-sustaining treatment is of particular importance. The subject matter is very relevant because of the alarming increase in multiple and preterm births, due to the increase in women who are undergoing assisted reproductive procedures, and the large increase in premature labor. No recent book covers the subject in such comparable breadth. The first section of this very timely monograph covers the epidemiology and practices in different parts of the world; the second section covers bioethics considerations, including ethical theories, moral principles and quality of life issues; the third section covers national and international guidelines; the last section covers medical law aspects in the US and around the world.

Following the success of three previous editions, this new edition of Newborn Surgery continues to provide the most comprehensive information on the surgical management of neonatal disorders. Each chapter is thoroughly revised and updated, and there are eight new chapters on key topics in the specialty, including neonatal care in the delivery room, specific risks for pre-term infants, surgical safety, tissue engineering and stem cell research, and surgical implications of HIV.

Neonatal Cerebral Investigation reviews all aspects of the investigation of the neonatal brain, bringing together diagnostic and prognostic information in a highly illustrated and practical text. An introductory section covers the basic principles of ultrasound, EEG, CFM and MR imaging and spectroscopy. These chapters are followed by a detailed review of normal neonatal imaging appearances and normal EEG, artefactual imaging appearances and imaging of various stages of the immature brain. Subsequent chapters discuss pre-term and term screening and review the imaging appearances in a variety of clinical conditions such as suspected seizure, suspected infection and enlarging head. Highly illustrated with over 400 ultrasound and MRI scans and EEG and CFM traces and providing detailed diagnostic and prognostic information on a wide range of clinical problems, Neonatal Cerebral Investigation provides the reader with a comprehensive overview of all aspects of investigation of the newborn baby with a potential neurological problem.

Babies of women with diabetes are nearly five times more likely to be stillborn and almost three times more likely to die in the first three months. The incidence of gestational diabetes mellitus in the U.S. is high-between 3 and 7 percent-and rising. The condition is often complicated by other risk factors such as obesity and heart disease. The Textbook of Diabetes and Pregnancy presents a comprehensive review of the science, clinical management, and medical implications of gestational diabetes mellitus, a condition with serious consequences that is on the increase in all developed societies. This new edition supports the latest initiatives and strategies of the International Federation of Gynecology and Obstetrics (FIGO) and adds chapters on noncommunicable diseases, obesity, bariatric surgery, and epidemiology outside Western cultures. Written by a cadre of experts, the book provides a comprehensive, authoritative, and international view of gestational diabetes mellitus and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and a growing number of gynecologists and general physicians concerned with the management of noncommunicable diseases in pregnancy.

This volume provides in a simple and concise format, all of the important information needed for advanced maternity care for primary care physicians including preconception counseling, prenatal care, medications in pregnancy, complications of pregnancy and labor. These issues and conditions are summarized without being overly detailed. This format provides an ease of use by primary care clinicians as various patient problems arise

Quick, one-stop guide to neonatal resuscitation steps.

Recent developments in diagnostic and therapeutic aspects of cardiac and neonatal issues have advanced the care of the newborn. In order to achieve excellence in cardiac care, however, close interaction and collaboration of the pediatric cardiologists with neonatologists, pediatricians, general/family practitioners (who care for children), anesthesiologists, cardiac surgeons, pediatric cardiac intensivists, and other subspecialty pediatricians is mandatory. This book provides the reader with up-to-date, evidence-based information in three major areas of neonatology and prenatal and neonatal cardiology. First, it offers an overview of advances in the disciplines of neonatology, prenatal and neonatal cardiology, and neonatal cardiac surgery in making early diagnosis and offering treatment options. Secondly, it presents a multidisciplinary approach to managing infants with congenital heart defects. Finally, it provides evidence-based therapeutic approaches to successfully treat the fetus and the newborn with important neonatal issues and congenital cardiac lesions.This second volume specifically explores issues related to individual cardiac defects, cardiomyopathies, and hypertension and presents a summary and conclusions of both volumes.