Birth is a sudden, traumatic transition of environments. Once the placental oxygen supply ceases, the foetus has only minutes to establish pulmonary oxygen transport, which requires not only inflation of the lungs, but also sudden and sustained changes in the lung circulation. Not long ago, research in this field was largely restricted to morphology and physiology. Now the powerful new tools of cellular and molecular biology have begun to
shed light on the physiological processes in the developing lung and its supporting vasculature.

In 22 chapters, three main sections explore lung growth and development, vascular cell growth and differentiation, and the mechanisms of hemodynamic control in the neonate; extensive illustrations give a comprehensive picture of pulmonary circulatory development. Factors controlling vasculogenesis and angiogenesis are described by the scientists who pioneered the field. Similarly, the intracellular signaling cascades that determine proliferation or growth inhibition of fibroblasts, smooth muscle cells, and endothelial cells are also presented in an understandable manner. Finally, the role of
substances, such as nitric oxide and endothelin, that control the hemodynamics of the fetal and neonatal circulations are discussed in detail, particularly in relation to the changes occurring at birth.

This book will inform basic scientists as well as the clinician and student, and should be of particular interest to pediatric cardiologists, pulmonary medicine physicians, and vascular biologists.

This book is an obstetric formulary, for doctors and others concerned with the medical care of pregnant women and their newborn babies. It provides specific prescribing information on the drugs necessary to the obstetric management of antenatal patients, women in labour and the puerpurium, and the newborn. It aims to be a readily available source of information for resident obstetric staff and family practitioners who undertake obstetrics. It is also intended to provide guidelines for specialist obstetricians in training their juniors in the safest and most effective ways of using drugs during pregnancy, and for midwives, nurses and pharmacists, who need to understand the drug treatment of pregnant women.;The prescribing sections of this handbook are restricted to agents of known safety and proven efficacy and as well as covering the use of drugs in pregnancy the book includes sections on the transfer of drugs into breast milk. Advice on diet, nursing care and physiotherapy are mentioned where relevant and an account of the procedures involved in providing an epidural service are included. Doses of drugs used for newborn babies are given in the last chapter.;A section on preconception counselling has been added to the second edition and the drugs included in the volume have been revised, some preparations which have become of value to obstetric practice have been added and some which have been found to have limited clinical value have been withdrawn. This edition has been adjusted so that the prescribing procedures are in line with those used in North America.

The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The book addresses this crucial interval of early life across biological disciplines, linking concepts related to all biological fields to outcomes during the first 1,000 days (e.g. fetal growth and pregnancy outcomes) and beyond (e.g. gut microbiome and cardiovascular disease later in life). The strength of this book lies in its cross-disciplinary nature.

Ein Screening auf angeborene endokrine und metabole Stoerungen ermoeglicht die Fruherkennung von Krankheiten wie Hypothyreose, AGS (adrenogenitales Syndrom), Phenylketonurie, Galaktosamie, Biotinidasemangel, Cystische Fibrose oder Homocystinurie. Je nach Land und politischen Bestimmungen unterscheiden sich jedoch die routinemassig durchgefuhrten Untersuchungen. Dieses Handbuch beschreibt praxisbezogen die biochemischen Grundlagen, die Grundsatze der Labor- und Bestatigungsdiagnostik sowie Therapiemoeglichkeiten zu insgesamt zwoelf Krankheiten. Daruber hinaus werden praanalytische Fragen, wie Zeitpunkt und Art der Blutentnahme oder moegliche Stoerfaktoren, umfassend behandelt. Der allgemeine Teil geht auf ethische und psychosoziale Aspekte des Screenings ein. Ein Verzeichnis der Screeningzentren und jener Labors, die fur die Bestatigungsdiagnostik Dienste anbieten, sowie ein Adressenverzeichnis von Elterngruppen und Informationsquellen im Internet komplettieren dieses Buch.

Many children spend their first days, weeks, and sometimes months in a neonatal intensive care unit as a consequence of prematurity, congenital anomalies, or birth complications. Their medical needs are thoughtfully appraised and attended to, yet some questions are rarely asked: What experiences do these newborns have? What experiences are we giving them? How can we and do we understand what their lives are like? What are the interventions and actions of medical care actually like for them? Michael van Manen explores the experiential life of newborn infants with particular consideration for those newborns who require medical care. Drawing on contemporary research findings from physiology, psychology, biology, and other disciplines, he offers phenomenological insights and raises thought-provoking questions as to how we ought to understand and care for such young children. In our contemporary world, it is often the experiences of inception, of first contact, with those who seem most distant, foreign, or even alien that we need to try to apprehend and understand. The inceptual lives of newborn infants challenges us to explore those experiences phenomenologically - to investigate the originary meanings of early life experiences. Phenomenology of the Newborn is an essential text for researchers seeking to employ phenomenology for the study of neonatal life and related concerns that may seem inaccessible to other more traditional qualitative and quantitative methods.

Who decides, and on what basis, how to treat a child with severe birth defects? Any decisions made on such cases are painful and complex, and have far-reaching consequences for society at large. Addressing the medical, legal, and ethical aspects of the issue, Robert Weir presents the first serious survey of the major arguments regarding selective non-treatment, which have been advanced by physicians, attorneys, and the judicial system.

The first resource of its kind, this authoritative handbook holistically addresses the multidimensional aspects of perinatal and neonatal palliative care. Written by an interprofessional team of renowned specialists, it is both a text and evidence-based reference for all members of the palliative care team. The book helps individual team members forge interdisciplinary approaches to care, assess current programs, improve the quality of care, and tailor new models of care.Encompassing the perspectives of neonatologists, maternal-fetal medicine and other physicians, neonatal and perinatal nurse practitioners, midwives, nurses in all sectors of perinatal care, and child life specialists, chaplains, social workers, genetic counselors, lactation consultants, and others, the book underscores the unique aspects of perinatal and neonatal palliative care, with a focus on improving quality of life, as well as comfort at the end of life. It describes healthcare for neonates and pregnant mothers, care and support of the family, planning and decision making, and effective support for grief and bereavement. It addresses all palliative and neonatal palliative care settings, including home care, and covers elements of comfort care, such as pain medication and oxygen. Other chapters focus on the prenatal period after diagnosis of the expected baby's life-threatening condition. These include such topics as care of the mother, delivering devastating news, and advance care planning. Each chapter contains photos, figures, and/or tables and case studies with clinical implications and critical thinking-focused questions. Some chapters also include supportive online materials, such as video clips of interactions between healthcare professionals and the family, demonstrating family support and clinician skills. Also included is an extensive listing of relevant palliative care organizations. Paintings and poetry provide an artistic backdrop to the authors' inspiring words. Key Features: Comprehensive and authoritative knowledge from recognized leaders in the field Addresses a growing need for specific provider resources in neonatal palliative care Covers the clinical and emotional aspects of palliative care for babies and their families Abundant resources for effective and compassionate family-centered care Case studies with critical thinking questions Accompanying video clips of healthcare and family interactions

Psychodynamic Interventions in Pregnancy and Infancy builds on Bjoern Salomonsson's experiences as a psychoanalytic consultant working with parents and their babies. Emotional problems during the perinatal stages can arise and be observed and addressed by a skilled midwife, nurse or health visitor. Salomonsson has developed a method combining nurse supervision and therapeutic consultations which has lowered the thresholds for parents to come and talk with him. The brief consultations concern pregnant women, mother and baby, husband and wife, toddler and parent. The theoretical framework is psychoanalytic, but the mode of work is eclectic and adapted to the family's situation and its members' motivation. This book details such work, which can be applied globally; perinatal psychotherapy integrated with ordinary medical health care. It also explains how psychotherapy can be made more accessible to a larger population. Via detailed case presentations, the author takes the reader through pregnancy, childbirth and the first few years of life. He also brings in research studies emphasizing the importance of early interventions, with the aim of providing therapists with arguments for such work in everyday family health care. To further substantiate such arguments, the book ends with theoretical chapters and, finally, the author's vision of the future of a perinatal health care that integrates medical and psychological perspectives. Psychodynamic Interventions in Pregnancy and Infancy will appeal to all psychoanalysts and psychoanalytic psychotherapists working in this area, as well as clinical psychologists, clinical social workers and medical personnel working with parents and infants.

Ein ubersichtliches Kompendium mit dem notwendigen Wissen fur die Ausbildung und tagliche Praxis: Mutterschaftsvorsorge, Vorbereitungskurse, risikofreie Geburt, Stillberatung, Elternschule oder Hausbesuche am Wochenbett. Neben den Grundlagen der regelrechten Geburt erlautert es Risikominimierung, Geburtsatmosphare, Schmerzausschaltung, Gebarhaltung sowie die Geburt unter Wasser. (Angehende) Hebammen in Klinik und Praxis finden hier viele Anregungen. Eine Lehrhebamme, eine in freier Praxis tatige Hebamme, eine Hebammenlehrerin und der arztliche Leiter einer Hebammenschule geben ihr Wissen weiter, das sie uber viele Jahre erworben haben."

Major advances in genetics, immunology, and endocrinology have necessitated a new edition of this best-selling text. However, despite the advances, recurrent pregnancy loss presents a frustrating clinical problem. There is still disagreement about the number of pregnancy losses which warrant investigation and treatment and about which investigations should be performed. This third edition provides an authoritative and comprehensive update on advances in the understanding and management of this troubling phenomenon, covering both basic scientific topics such as genetics and cytokines, and profiles major advances in immunology, endocrinology, and thrombotic mechanism. Clinical research is discussed, as is assessment of results when applying an evidence-based approach or a more personalised approach, which is now becoming possible due to advances in the diagnosis of cause. There are lively debates on the role of progestogens and immunotherapy, which remain controversial. Designed for specialists working in reproductive medicine clinics and those involved with maternal-fetal care, the book is also ideal for generalists and gynecologists seeking a comprehensive view of developments in the field.

Thoroughly revised and updated, this new edition of Neonatal Intensive Care Nursing is a comprehensive, evidence-based text for nurses and allied health professionals caring for sick newborn infants. This user-friendly text focuses on the common problems and related care occurring within the neonatal specialty. All previous chapters have been thoroughly updated and new content includes chapters on, for example, organisation of neonatal care, assessment of the neonate, the premature and low birth weight neonate as well as palliative care. In addition, the book now includes a broad and in-depth web-based companion comprising online resources, case studies with answer guides and learning activities. This accessible and interactive approach enables nurses to recognise, rationalise and understand clinical problems using an evidence-based approach. Divided into four parts, the book provides an overview of neonatal care, and a detailed look at the physical and emotional wellbeing of neonate and family, a range of clinical aspects of neonatal care, and key practices and procedures. Neonatal Intensive Care Nursing will be essential reading for both new and experienced nurses, allied health professionals and students learning about neonatal care including those undertaking qualifications in the neonatal specialism and pre-registration students taking relevant modules or placements.

Although there are far more opportunities for LGBTQ people to become parents than there were before the 1990s, attention to the reproductive challenges LGBTQ families face has not kept pace. Reproductive Losses considers LGBTQ people's experiences with miscarriage, stillbirth, failed adoptions, infertility, and sterility. Drawing on Craven's training as a feminist anthropologist and her experiences as a queer parent who has experienced loss, Reproductive Losses includes detailed stories drawn from over fifty interviews with LGBTQ people (including those who carried pregnancies, non-gestational and adoptive parents, and families from a broad range of racial/ethnic, socio-economic, and religious backgrounds) to consider how they experience loss, grief, and mourning. The book includes productive suggestions and personal narratives of resiliency, commemorative strategies, and communal support, while also acknowledging the adversity many LGBTQ people face as they attempt to form families and the heteronormativity of support resources for those who have experienced reproductive loss. This is essential reading for scholars and professionals interested in LGBTQ health and family, and for individuals in LGBTQ communities who have experienced loss and those who support them. See additional material on the companion website: www.lgbtqreproductiveloss.org/

Pregnancy complicated by neurological disorders is a challenging area for both Obstetricians and Neurologists. Treatment of the maternal condition often needs to be adjusted because of concerns for the fetus, and some conditions will have a major impact on the method, mode and timing of delivery. Many of the clinical problems that arise in pregnant women with neurological disease have not been the subject of clinical trials, so management must often be based on what published evidence is available and a good understanding of the likely interactions between the condition and pregnancy and vice versa.

The editors and contributors represent a team with considerable experience in this area. They offer their best practice advice as how to treat the mother effectively, ensuring fetal safety, as well as embracing a philosophy that the pregnancy of a woman with neurological disease should be made as enjoyable and rewarding for her as is possible.

?er 1000 Stichworte: Wer schnelle Information ?er Krankheitsbilder, Ursachen, Symptome, Behandlung und Vorbeugung sucht, findet hier verst?dliche Antworten und Rat.

"
What makes us the "w"ay "w"e are? "Some say it's the genes we inherit at conception. Others are sure it's the environment we experience in childhood. But could it be that many of our individual characteristics--our health, our intelligence, our temperaments--are influenced by the conditions we encountered before birth?
That's the claim of an exciting and provocative field known as fetal origins. Over the past twenty years, scientists have been developing a radically new understanding of our very earliest experiences and how they exert lasting effects on us from infancy well into adulthood. Their research offers a bold new view of pregnancy as a crucial staging ground for our health, ability, and well-being throughout life.
Author and journalist Annie Murphy Paul ventures into the laboratories of fetal researchers, interviews experts from around the world, and delves into the rich history of ideas about how we're shaped before birth. She discovers dramatic stories: how individuals gestated during the Nazi siege of Holland in World War II are still feeling its consequences decades later; how pregnant women who experienced the 9/11 attacks passed their trauma on to their offspring in the womb; how a lab accident led to the discovery of a common household chemical that can harm the developing fetus; how the study of a century-old flu pandemic reveals the high personal and societal costs of poor prenatal experience.
"
Origins "also brings to light astonishing scientific findings: how a single exposure to an environmental toxin may produce damage that is passed on to multiple generations; how conditions as varied as diabetes, heart disease, and mental illness may get their start in utero; why the womb is medicine's latest target for the promotion of lifelong health, from preventing cancer to reducing obesity. The fetus is not an inert being, but an active and dynamic creature, responding and adapting as it readies itself for life in the particular world it will enter. The pregnant woman is not merely a source of potential harm to her fetus, as she is so often reminded, but a source of influence on her future child that is far more powerful and positive than we ever knew. And pregnancy is not a nine-month wait for the big event of birth, but a momentous period unto itself, a cradle of individual strength and wellness and a crucible of public health and social equality.
With the intimacy of a personal memoir and the sweep of a scientific revolution, "Origins "presents a stunning new vision of our beginnings that will change the way you think about yourself, your children, and human nature itself.

The only text to provide in-depth illustrations of the normal and abnormal fetal anatomy on MR imaging, this guide includes chapters highlighting the state-of-the-science in the imaging of the fetal skull, face, neck, nervous system, chest, abdomen, and musculoskeletal system. Discussing applications at the forefront of the discipline, this reference studies data gleaned from MR examinations of maternal and fetal health, reviews common fast imaging techniques, details pitfalls related to fetal MR imaging, and analyzes methods for improving image resolution.

As research in neuroscience increasingly points to the unparalleled influence of the first 1000 days of life from conception to two years of age in determining the baby's life trajectory, the need for high-quality early parenting education delivered by knowledgeable and dedicated professionals becomes ever more apparent. This book describes the global aims of early parenting education. It identifies the key areas that research suggests are important: building a relationship with the unborn and newborn baby; preparing for labour and birth; supporting parents' mental health; protecting the couple relationship across the transition to parenthood; and education for special groups such as same-sex couples, women with fear of birth, prisoners, military wives and parents from black and minority ethnic backgrounds. All practitioners providing early parenting programmes - midwives, health visitors, family link workers, children's centre staff and voluntary sector teachers - will gain new ideas for their practice in this book. Students taking midwifery and early childhood courses will find much to support their studies. Ultimately, the book provides inspiration for all those who are committed to the role of parenting education in reducing social inequalities.

Although there is an increasing number of pregnant individuals taking nutraceuticals to maintain good health, many gaps exist in the knowledge base. These nutraceuticals might be involved in a wide variety of biological processes, and the biological and epidemiological findings of relevant studies should be examined and analyzed. Nutraceuticals for Prenatal, Maternal and Offspring's Nutritional Health focuses on the role of nutraceuticals for prenatal, mothers, and offspring's health. In recent years, new trends have been established in this area of prenatal nutrition, that is, mother and offspring health based on appropriate nutrition during pre-pregnancy, pregnancy, and after pregnancy. Nutraceuticals and natural products have been used by many cultures and societies around the world. This book focuses on recent trends and potential clinical evaluations of such nutraceuticals and natural products. Features: Examines the role of Nutraceuticals on the mothers and offspring's disease and health Focuses on human population-based research Discuses role of nutraceuticals in placental development, nutraceuticals for gestational weight pain and post-partum obesity Covers nutraceuticals impacting uterine growth, gestational age, and mortality rate Explores the question whether Nutraceuticals intake in pregnant women is safe as they might be involved a wide variety of biological processes With 19 chapters written by established lead authors in this field, Nutraceuticals for Prenatal, Maternal and Offspring's Nutritional Health addresses important findings of the latest scientific research regarding the role of nutraceuticals intake before and during pregnancy.

It is only in recent years that there has been development in the awareness of the father's mental health. Yet, the father's mental health can influence the mother, the infant, the family and society. This book seeks to address the reasons why the father or the potential father could suffer from a mental disorder or illness during the perinatal period, his reactions, and what can be done to help him. The book explores the way in which fathers' mental health has presented in the past and how it presents now. It looks at the father's attitudes towards his mental well-being and how he may self-manage and self-medicate. It examines the impact and influence the potential father and the father's mental health has on his partner, infant and children. The reasons for certain disorders and illnesses are outlined, along with how they may manifest and are managed. Treatment options and types of medication are discussed and the ways in which the father can access the best possible help and support. Stories from fathers who have suffered from a particular mental illness or condition help others to understand both the practicalities and realities. The uniqueness of the shared stories from fathers highlights why recognition treatment and management are important to help other fathers improve their relationship with their partner and infant and to improve their own wellbeing. The book is intended to help health practitioners and anyone who is concerned about fathers' mental health.

This concise guide offers a comprehensive step-by-step framework for midwifery students to learn about all aspects of the newborn infant physical examination (NIPE), a screening assessment completed on all babies between 6 and 72 hours of age. The Student Guide to the Newborn Infant Physical Examination encourages the reader to approach the examination in a system-based format, with case studies and practice tips to support learning. The book offers: * Evidence-based, well-illustrated assessment tools, which take into account the national screening committee standards, and is written by authors with both academic and clinical experience; * A clear direction on how to perform the NIPE in practice while exploring the wider context of screening in healthcare today; * Coverage of the changing role of the midwife, and the importance of understanding the whole context of the mother's care, health promotion and starting the practitioner-parent conversation. The Student Guide to the Newborn Infant Physical Examination is a core text for all pre-registration midwifery students and a useful resource for qualified midwives, neonatal nurses and practice nurses.

This concise guide offers a comprehensive step-by-step framework for midwifery students to learn about all aspects of the newborn infant physical examination (NIPE), a screening assessment completed on all babies between 6 and 72 hours of age. The Student Guide to the Newborn Infant Physical Examination encourages the reader to approach the examination in a system-based format, with case studies and practice tips to support learning. The book offers: * Evidence-based, well-illustrated assessment tools, which take into account the national screening committee standards, and is written by authors with both academic and clinical experience; * A clear direction on how to perform the NIPE in practice while exploring the wider context of screening in healthcare today; * Coverage of the changing role of the midwife, and the importance of understanding the whole context of the mother's care, health promotion and starting the practitioner-parent conversation. The Student Guide to the Newborn Infant Physical Examination is a core text for all pre-registration midwifery students and a useful resource for qualified midwives, neonatal nurses and practice nurses.

The most common abnormal growth of the female reproductive system, fibroids, are thought to affect the majority of women at some point during their reproductive years. This text from leading fibroid experts looks at the latest evidence on how the problem impinges on reproduction and the most up-to-date management and treatment options available to help patients with fibroids hoping to conceive. Print versions of this book also include access to the eBook version with links to procedural videos.

This book is a practical guide for medical practitioners as they navigate through breastfeeding problems that occur in day-to-day practice. If mothers have a breastfeeding complication they are often directed to their GP. In complex situations, medical staff will be making decisions around what treatment plan to follow and whether a mother can keep breastfeeding. In recent years there has been growing evidence that medical professionals often advise mothers to stop breastfeeding while undergoing treatment, when in reality this was not a necessary step. In a time when breastfeeding rates are decreasing, it is important that medical professionals give accurate advice and support a mother's choice to breastfeed if the situation allows it. A Guide to Supporting Breastfeeding for the Medical Profession includes contributions from a wide range of medical professionals and each chapter is written with the practitioner in mind. Contributors include GPs, paediatricians, neonatologists, lactation specialists and midwives. Doctors have a vital role to play in supporting and facilitating breastfeeding, and without the appropriate knowledge they can often inadvertently sabotage it. This book will be of interest to GPs and paediatricians as well as nurse prescribers, midwives and health visitors.

This book contains a series of clinical cases that address and illustrate difficult problems in obstetric ultrasound. The approach is strongly didactic and will aid trainees in maternal-fetal medicine and obstetrics to appreciate potential pitfalls and recognize rare presentations. Each case sets out one page of text, then one of treatment algorithms, and then presents sample ultrasound scans. Learning objectives are given for each case, together with a short list of references and background reading.

Although there are far more opportunities for LGBTQ people to become parents than there were before the 1990s, attention to the reproductive challenges LGBTQ families face has not kept pace. Reproductive Losses considers LGBTQ people's experiences with miscarriage, stillbirth, failed adoptions, infertility, and sterility. Drawing on Craven's training as a feminist anthropologist and her experiences as a queer parent who has experienced loss, Reproductive Losses includes detailed stories drawn from over fifty interviews with LGBTQ people (including those who carried pregnancies, non-gestational and adoptive parents, and families from a broad range of racial/ethnic, socio-economic, and religious backgrounds) to consider how they experience loss, grief, and mourning. The book includes productive suggestions and personal narratives of resiliency, commemorative strategies, and communal support, while also acknowledging the adversity many LGBTQ people face as they attempt to form families and the heteronormativity of support resources for those who have experienced reproductive loss. This is essential reading for scholars and professionals interested in LGBTQ health and family, and for individuals in LGBTQ communities who have experienced loss and those who support them. See additional material on the companion website: www.lgbtqreproductiveloss.org/