Unmanned air vehicles are becoming increasingly popular alternatives for private applications which include, but are not limited to, fire fighting, search and rescue, atmospheric data collection, and crop surveys, to name a few. Among these vehicles are avian-inspired, flapping-wing designs, which are safe to operate near humans and are required to carry payloads while achieving manoeuverability and agility in low speed flight. Conventional methods and tools fall short of achieving the desired performance metrics and requirements of such craft. Flight dynamics and system identification for modern feedback control provides an in-depth study of the difficulties associated with achieving controlled performance in flapping-wing, avian-inspired flight, and a new model paradigm is derived using analytical and experimental methods, with which a controls designer may then apply familiar tools. This title consists of eight chapters and covers flapping-wing aircraft and flight dynamics, before looking at nonlinear, multibody modelling as well as flight testing and instrumentation. Later chapters examine system identification from flight test data, feedback control and linearization.
Presents experimental flight data for validation and verification of modelled dynamics, thus illustrating the deficiencies and difficulties associated with modelling flapping-wing flightDerives a new flight dynamics model needed to model avian-inspired vehicles, based on nonlinear multibody dynamicsExtracts aerodynamic models of flapping flight from experimental flight data and system identification techniques

Radioactive waste management and contaminated site clean-up reviews radioactive waste management processes, technologies, and international experiences. Part one explores the fundamentals of radioactive waste including sources, characterisation, and processing strategies. International safety standards, risk assessment of radioactive wastes and remediation of contaminated sites and irradiated nuclear fuel management are also reviewed. Part two highlights the current international situation across Africa, Asia, Europe, and North America. The experience in Japan, with a specific chapter on Fukushima, is also covered. Finally, part three explores the clean-up of sites contaminated by weapons programmes including the USA and former USSR.
Radioactive waste management and contaminated site clean-up is a comprehensive resource for professionals, researchers, scientists and academics in radioactive waste management, governmental and other regulatory bodies and the nuclear power industry.
Explores the fundamentals of radioactive waste including sources, characterisation, and processing strategiesReviews international safety standards, risk assessment of radioactive wastes and remediation of contaminated sites and irradiated nuclear fuel managementHighlights the current international situation across Africa, Asia, Europe, and North America specifically including a chapter on the experience in Fukushima, Japan

Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.
Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.
With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.
Provides an overview of the current and potential future use of metabolomics in the food industryChapters focus on key applications and review the analytical methods used and the bioinformatics techniques involved in processing the resultsDiscusses metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications

"Primer on Flat Rolling" is a fully revised second edition, and the outcome of over three decades of involvement with the rolling process. It is based on the author's yearly set of lectures, delivered to engineers and technologists working in the rolling metal industry. The essential and basic ideas involved in designing and analysis of the rolling process are presented.

The book discusses and illustrates in detail the three components of flat rolling: the mill, the rolled metal, and their interface. New processes are also covered; flexible rolling and accumulative roll-bonding. The last chapter contains problems, with solutions that illustrate the complexities of flat rolling.

New chapters include a study of hot rolling of aluminum, contributed by Prof. M. Wells; advanced applications of the finite element method, by Dr. Yuli Liu and by Dr. G. Krallics; roll design by Dr. J. B. Tiley and the history of the development of hot rolling mills, written by Mr. D. R. Adair and E. B. Intong.

Engineers, technologists and students can all use this book to aid their planning and analysis of flat rolling processes.
Provides clear descriptions for engineers and technologists working in steel millsEvaluates the predictive capabilities of mathematical modelsAssignments and their solutions are included within the text

The response of concrete under tensile loading is crucial for most applications because concrete is much weaker in tension than in compression. Understanding the response mechanisms of concrete under tensile conditions is therefore key to understanding and using concrete in structural applications. Understanding the tensile properties of concrete summarises key recent research in this important subject.
After an introduction to concrete, the book is divided into two parts: part one on static response and part two on dynamic response. Part one starts with a summary chapter on the most important parameters that affect the tensile response of concrete. Chapters show how multi scale modelling is used to relate concrete composition to tensile properties. Part two focuses on dynamic response and starts with an introduction to the different regimes of dynamic loading, ranging from the low frequency loading by wind or earthquakes up to the extreme dynamic conditions due to explosions and ballistic impacts. Following chapters review dynamic testing techniques and devices that deal with the various regimes of dynamic loading. Later chapters highlight the dynamic behaviour of concrete from different viewpoints, and the book ends with a chapter on practical examples of how detailed knowledge on tensile properties is used by engineers in structural applications.
Drawing on the work of some of the leading experts in the field, Understanding the tensile properties of concrete is a valuable reference for civil and structural engineers as well as those researching this important material.
Summarises key recent research in the areas of understanding the response mechanisms of concrete under tensile conditionsProvides a summary of the most important parameters that affect the tensile response of concrete and shows how multi scale modeling is used to relate concrete composition to tensile propertiesHighlights the dynamic behaviour of concrete from different viewpoints and provides practical examples of how detailed knowledge on tensile properties is used by engineers in structural applications

Since its first development in the 1970s, Process Integration (PI) has become an important methodology in achieving more energy efficient processes. This pioneering handbook brings together the leading scientists and researchers currently contributing to PI development, pooling their expertise and specialist knowledge to provide readers with a comprehensive and up-to-date guide to the latest PI research and applications.
After an introduction to the principles of PI, the book reviews a wide range of process design and integration topics ranging from heat and utility systems to water, recycling, waste and hydrogen systems. The book considers Heat Integration, Mass Integration and Extended PI as well as a series of applications and case studies. Chapters address not just operating and capital costs but also equipment design and operability issues, through to buildings and supply chains.
With its distinguished editor and international team of expert contributors, Handbook of Process Integration (PI) is a standard reference work for managers and researchers in all energy-intensive industries, as well as academics with an interest in them, including those designing and managing oil refineries, petrochemical and power plants, as well as paper/pulp, steel, waste, food and drink processors.
This pioneering handbook provides a comprehensive and up-to-date guide to the latest process integration research and applicationsReviews a wide range of process design and integration topics ranging from heat and utility systems to water, recycling, waste and hydrogen systemsChapters also address equipment design and operability issues, through to buildings and supply chains

The Handbook of Equine Emergencies is a concise, easy-to-follow practical guide to how to deal with a range of equine emergencies likely to be encountered by clinicians both in the UK and abroad. It is primarily aimed at new graduates and veterinarians who do not deal with equine emergencies on a regular basis, but will also appeal to more experienced equine practitioners who want a quick update on a specific subject area or practical technique. The Handbook is highly portable and contains a large number of colour images, diagrams and tables as well as handy tips and key points to remember. An overview of the basics of dealing with equine emergencies is followed by a convenient organ-based approach. The book includes invaluable information on infectious diseases and specialized emergency situations such as trapped horses or stable fires, and a how-to section gives concise but detailed descriptions of how to perform a number of diagnostic investigations. The Handbook is accompanied by a mobile-optimized website that presents audio, video and text files for quick reprisal via phone or tablet while on-the-go. The website also includes additional colour images that are relevant to specific emergency situations covered in the book. Suitable for all veterinary clinicians seeing horses Concise and practical layout and content Videos, audio, text summaries and images all accessible via your mobile device More than 150 full colour unique images

The increased use of polymer matrix composites in structural applications has led to the growing need for a very high level of quality control and testing of products to ensure and monitor performance over time. Non-destructive evaluation (NDE) of polymer matrix composites explores a range of NDE techniques and the use of these techniques in a variety of application areas.
Part one provides an overview of a range of NDE and NDT techniques including eddy current testing, shearography, ultrasonics, acoustic emission, and dielectrics. Part two highlights the use of NDE techniques for adhesively bonded applications. Part three focuses on NDE techniques for aerospace applications including the evaluation of aerospace composites for impact damage and flaw characterisation. Finally, the use of traditional and emerging NDE techniques in civil and marine applications is explored in part four.
With its distinguished editor and international team of expert contributors, Non-destructive evaluation (NDE) of polymer matrix composites is a technical resource for researchers and engineers using polymer matrix composites, professionals requiring an understanding of non-destructive evaluation techniques, and academics interested in this field.
Explores a range of NDE and NDT techniques and considers future trendsExamines in detail NDE techniques for adhesively bonded applicationsDiscusses NDE techniques in aerospace applications including detecting impact damage, ultrasonic techniques and structural health monitoring

Algae have a long history of use as foods and for the production of food ingredients. There is also increasing interest in their exploitation as sources of bioactive compounds for use in functional foods and nutraceuticals. Functional ingredients from algae for foods and nutraceuticals reviews key topics in these areas, encompassing both macroalgae (seaweeds) and microalgae.
After a chapter introducing the concept of algae as a source of biologically active ingredients for the formulation of functional foods and nutraceuticals, part one explores the structure and occurrence of the major algal components. Chapters discuss the chemical structures of algal polysaccharides, algal lipids, fatty acids and sterols, algal proteins, phlorotannins, and pigments and minor compounds. Part two highlights biological properties of algae and algal components and includes chapters on the antioxidant properties of algal components, anticancer agents derived from marine algae, anti-obesity and anti-diabetic activities of algae, and algae and cardiovascular health. Chapters in part three focus on the extraction of compounds and fractions from algae and cover conventional and alternative technologies for the production of algal polysaccharides. Further chapters discuss enzymatic extraction, subcritical water extraction and supercritical CO2 extraction of bioactives from algae, and ultrasonic- and microwave-assisted extraction and modification of algal components. Finally, chapters in part four explore applications of algae and algal components in foods, functional foods and nutraceuticals including the design of healthier foods and beverages containing whole algae, prebiotic properties of algae and algae-supplemented products, algal hydrocolloids for the production and delivery of probiotic bacteria, and cosmeceuticals from algae.
Functional ingredients from algae for foods and nutraceuticals is a comprehensive resource for chemists, chemical engineers and medical researchers with an interest in algae and those in the algaculture, food and nutraceutical industries interested in the commercialisation of products made from algae.
Provides an overview of the major compounds in algae, considering both macroalgae (seaweeds) and microalgaeDiscusses methods for the extraction of bioactives from algaeDescribes the use of algae and products derived from them in the food and nutraceutical industries

This book is the first comprehensive treatment of the major ethical and social issues resulting from the use of ionizing radiation. It covers topics such as nuclear fuel cycles, radioactive waste treatment, nuclear bomb testing, nuclear safety management, stakeholder engagement, cleanup after nuclear accidents, ecological risks from radiation, environmental justice, health and safety for radiation workers, radiation dose standards, the ethics of clinical radiology, and the principles of radiation protection and their ethical underpinnings. With authors ranging from philosophers to radiation protection officials and practitioners, the book spans from theoretical to practical implications of this important area of radiation risk assessment and management.
Covers all the major social and ethical issues in relation to radiation protectionInformation is easily accessible and non-technicalAuthors include leading radiation protection officials as well as specialists who are more independent of the radiation protection system, thus presenting both authoritative and more critical viewsIncludes theoretical perspectives as well as practical experience

By some measure the most widely produced chemical in the world today, sulfuric acid has an extraordinary range of modern uses, including phosphate fertilizer production, explosives, glue, wood preservative and lead-acid batteries. An exceptionally corrosive and dangerous acid, production of sulfuric acid requires stringent adherence to environmental regulatory guidance within cost-efficient standards of production.

This work provides an experience-based review of how sulfuric acid plants work, how they should be designed and how they should be operated for maximum sulfur capture and minimum environmental impact. Using a combination of practical experience and deep physical analysis, Davenport and King review sulfur manufacturing in the contemporary world where regulatory guidance is becoming ever tighter (and where new processes are being required to meet them), and where water consumption and energy considerations are being brought to bear on sulfuric acid plant operations. This 2e will examine in particular newly developed acid-making processes and new methods of minimizing unwanted sulfur emissions.

The target readers are recently graduated science and engineering students who are entering the chemical industry and experienced professionals within chemical plant design companies, chemical plant production companies, sulfuric acid recycling companies and sulfuric acid users. They will use the book to design, control, optimize and operate sulfuric acid plants around the world.

Unique mathematical analysis of sulfuric acid manufacturing processes, providing a sound basis for optimizing sulfuric acid manufacturing processes.

Analysis of recently developed sulfuric acid manufacturing techniques suggestsadvantages and disadvantages of the new processes from the energy and environmental points of view.

Analysis of tail gas sulfur capture processes indicates the best way to combine sulfuric acid making and tailgas sulfur-capture processes from the energy and environmental points of view.

Draws on industrial connections of the authors through years of hands-on experience in sulfuric acid manufacture. "

Geological storage and sequestration of carbon dioxide, in saline aquifers, depleted oil and gas fields or unminable coal seams, represents one of the most important processes for reducing humankind s emissions of greenhouse gases. Geological storage of carbon dioxide (CO2) reviews the techniques and wider implications of carbon dioxide capture and storage (CCS).
Part one provides an overview of the fundamentals of the geological storage of CO2. Chapters discuss anthropogenic climate change and the role of CCS, the modelling of storage capacity, injectivity, migration and trapping of CO2, the monitoring of geological storage of CO2, and the role of pressure in CCS. Chapters in part two move on to explore the environmental, social and regulatory aspects of CCS including CO2 leakage from geological storage facilities, risk assessment of CO2 storage complexes and public engagement in projects, and the legal framework for CCS. Finally, part three focuses on a variety of different projects and includes case studies of offshore CO2 storage at Sleipner natural gas field beneath the North Sea, the CO2CRC Otway Project in Australia, on-shore CO2 storage at the Ketzin pilot site in Germany, and the K12-B CO2 injection project in the Netherlands.
Geological storage of carbon dioxide (CO2) is a comprehensive resource for geoscientists and geotechnical engineers and academics and researches interested in the field.
Reviews the techniques and wider implications of carbon dioxide capture and storage (CCS)An overview of the fundamentals of the geological storage of CO2 discussing the modelling of storage capacity, injectivity, migration and trapping of CO2 among other subjectsExplores the environmental, social and regulatory aspects of CCS including CO2 leakage from geological storage facilities, risk assessment of CO2 storage complexes and the legal framework for CCS"

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.
The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.
This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.
A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancerDiscusses the fundamentals of biomaterials for cancer therapeuticsDiscusses synthetic vaccines, proteins and polymers for cancer therapeutics

Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public. They persist in the environment, accumulate in food chains and may adversely affect human health if ingested over certain levels or with prolonged exposure. Persistent organic pollutants and toxic metals in foods explores the scientific and regulatory challenges of ensuring that our food is safe to eat.
Part one provides an overview of regulatory efforts to screen, monitor and control persistent organic pollutants and heavy metals in foods and includes case studies detailing regulatory responses to food contamination incidents. Part two moves on to highlight particular POPs, toxic metals and metalloids in foods, including dioxins and polychlorinated biphenyls (PCBs), mercury, polycyclic aromatic hydrocarbons (PAHs) and phthalates.
Persistent organic pollutants and toxic metals in foods is a standard reference for those in the food industry responsible for food safety, laboratories testing for food chemical safety, regulatory authorities responsible for ensuring the safety of food, and researchers in industry and academia interested in the science supporting food chemical safety.
Includes case studies which detail regulatory responses to food contamination incidentsConsiders the uptake and transfer of persistent organic pollutants in the food chain and the risk assessment of contaminates in foodDetails perticular persistent organic pollutants, toxic metals and metalloids in foods including polychlorinated biphenyls (PCBs), per- and polyfluoroalkyl substances (PFASs), mercury and arsenic among others

This authoritative and comprehensive book makes the reader familiar with the processes of bringing orphan drugs to the global market. There are between 5,000 and 7,000 rare diseases and the number of patients suffering from them is estimated to be more than 50 million in the US and Europe. Before the orphan drug legislation enacted in the US in 1983, there was a limited interest from industry to develop treatment for very small patient groups. One of the difficulties is, of course, that similar levels of investment are needed from a pharmaceutical company to bring a drug to the market for both small and large patient groups.
The journey from application of an orphan drug designation to a reimbursed market- approved drug is long and many obstacles occur during the journey.
After reading the book, readers will: Understand who the players/stakeholders are in the rare orphan disease field and their specific needs and concerns: patients and patient organizations, researchers and treating physicians within the field, industry, regulatory and reimbursement bodies* Understand the strong partnership between the different players and the various initiatives to improve and increase access to treatment for patients; minimizing the gap between numbers of known diseases, orphan designations, approved drugs and paid drugs.
The book also provides short practical case stories from patients and researchers, as well as representatives from industry and authorities on the challenges they came across in developing orphan drugs or getting access to orphan drugs.
A comprehensive overview of strategy, key activities and considerations of how to bring an orphan drug from concept to the market and make it available to patientsA source of updated information, news and trends for those who are already active in this fast-evolving fieldCovers the global definitions and the criteria for getting an orphan drug designation in, for example, the US and Europe

With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful.
Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing.
A focus on the issues associated with the application of lean principles to biomanufacturingPractical examples of factors which can affect biopharmaceutical processesCoverage of key factors which require integration to run an efficient biopharmaceutical process

Semiconductor lasers have important applications in numerous fields, including engineering, biology, chemistry and medicine. They form the backbone of the optical telecommunications infrastructure supporting the internet, and are used in information storage devices, bar-code scanners, laser printers and many other everyday products. Semiconductor lasers: Fundamentals and applications is a comprehensive review of this vital technology.
Part one introduces the fundamentals of semiconductor lasers, beginning with key principles before going on to discuss photonic crystal lasers, high power semiconductor lasers and laser beams, and the use of semiconductor lasers in ultrafast pulse generation. Part two then reviews applications of visible and near-infrared emitting lasers. Nonpolar and semipolar GaN-based lasers, advanced self-assembled InAs quantum dot lasers and vertical cavity surface emitting lasers are all considered, in addition to semiconductor disk and hybrid silicon lasers. Finally, applications of mid- and far-infrared emitting lasers are the focus of part three. Topics covered include GaSb-based type I quantum well diode lasers, interband cascade and terahertz quantum cascade lasers, whispering gallery mode lasers and tunable mid-infrared laser absorption spectroscopy.
With its distinguished editors and international team of expert contributors, Semiconductor lasers is a valuable guide for all those involved in the design, operation and application of these important lasers, including laser and telecommunications engineers, scientists working in biology and chemistry, medical practitioners, and academics working in this field.
Provides a comprehensive review of semiconductor lasers and their applications in engineering, biology, chemistry and medicineDiscusses photonic crystal lasers, high power semiconductor lasers and laser beams, and the use of semiconductor lasers in ultrafast pulse generationReviews applications of visible and near-infrared emitting lasers and mid- and far-infrared emitting lasers

Cereals are a staple of the human diet and have a significant effect on health. As a result, they are of major significance to the food industry. Cereal grains for the food and beverage industries provides a comprehensive overview of all of the important cereal and pseudo-cereal species, from their composition to their use in food products.
The book reviews the major cereal species, starting with wheat and triticale before covering rye, barley and oats. It goes on to discuss other major species such as rice, maize, sorghum and millet, as well as pseudo-cereals such as buckwheat, quinoa and amaranth. Each chapter reviews grain structure, chemical composition (including carbohydrate and protein content), processing and applications in food and beverage products.
Cereal grains for the food and beverage industries is an essential reference for academic researchers interested in the area of cereal grains and products. It is also an invaluable reference for professionals in the food and beverage industry working with cereal products, including ingredient manufacturers, food technologists, nutritionists, as well as policy-makers and health care professionals.
A comprehensive overview of all of the important cereal and pseudo-cereal speciesChapters review each of the following species: Wheat, Maize, Rice, Barley, Triticale, Rye, Oats, Sorghum, Millet, Teff, Buckwheat, Quinoa and AmaranthReviews grain structure, chemical composition, processing and applications in food and beverage products for each of the considered grains

The utilisation of biomass is increasingly important for low- or zero-carbon power generation. Developments in conventional power plant fuel flexibility allow for both direct biomass combustion and co-firing with fossil fuels, while the integration of advanced technologies facilitates conversion of a wide range of biomass feedstocks into more readily combustible fuel. Biomass combustion science, technology and engineering reviews the science and technology of biomass combustion, conversion and utilisation.
Part one provides an introduction to biomass supply chains and feedstocks, and outlines the principles of biomass combustion for power generation. Chapters also describe the categorisation and preparation of biomass feedstocks for combustion and gasification. Part two goes on to explore biomass combustion and co-firing, including direct combustion of biomass, biomass co-firing and gasification, fast pyrolysis of biomass for the production of liquids and intermediate pyrolysis technologies. Largescale biomass combustion and biorefineries are then the focus of part three. Following an overview of large-scale biomass combustion plants, key engineering issues and plant operation are discussed, before the book concludes with a chapter looking at the role of biorefineries in increasing the value of the end-products of biomass conversion.
With its distinguished editor and international team of expert contributors, Biomass combustion science, technology and engineering provides a clear overview of this important area for all power plant operators, industrial engineers, biomass researchers, process chemists and academics working in this field.
Reviews the science and technology of biomass combustion, conversion and utilisationProvides an introduction to biomass supply chains and feedstocks and outlines the principles of biomass combustion for power generationDescribes the categorisation and preparation of biomass feedstocks for combustion and gasification

A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools.
Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software.
Coverage of artificial intelligence tools, new expert systems, understanding of pharmaceutical processes, robust development of medicines, and new ways to develop medicinesDevelopment of drugs and medicines using mathematical toolsCompilation of expert system developed around the world

'Seven a.m.
What the hell is going on?
The ringing turns into pounding.
Halfway to the door, he hesitates, moves to the window, peers out.
His stomach drops.
Tesla has found him.'

When an anonymous whistleblower and ex-Tesla employee approached the German business newspaper Handelsblatt in November 2022, its newsroom was stunned.

The allegations were astounding, offering an unprecedented glimpse inside the world’s most secretive and impenetrable automaker.

So began a relentless pursuit for truth in an investigation to piece together the inner workings of Musk’s empire. What emerged was a company that values hype over substance; at its heart a CEO who demands devotion and rules through fear.

A riveting behind-the-scenes chronicle of fearless investigative journalism and an astonishing exposé of what lies under the bonnet of the world’s most famous car company, The Tesla Files is the story of what happens when the line between tech empire and political power blurs, and the gripping account of what it takes to challenge the richest man in the world.

Bacteria, yeast, fungi and microalgae can act as producers (or catalysts for the production) of food ingredients, enzymes and nutraceuticals. With the current trend towards the use of natural ingredients in foods, there is renewed interest in microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins. Microbial production of substances such as organic acids and hydrocolloids also remains an important and fast-changing area of research. Microbial production of food ingredients, enzymes and nutraceuticals provides a comprehensive overview of microbial production of food ingredients, enzymes and nutraceuticals.
Part one reviews developments in the metabolic engineering of industrial microorganisms and advances in fermentation technology in the production of fungi, yeasts, enzymes and nutraceuticals. Part two discusses the production and application in food processing of substances such as carotenoids, flavonoids and terponoids, enzymes, probiotics and prebiotics, bacteriocins, microbial polysaccharides, polyols and polyunsaturated fatty acids.
Microbial production of food ingredients, enzymes and nutraceuticals is an invaluable guide for professionals in the fermentation industry as well as researchers and practitioners in the areas of biotechnology, microbiology, chemical engineering and food processing.
Provides a comprehensive overview of microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocinsBegins with a review of key areas of systems biology and metabolic engineering, including methods and developments for filamentous fungiAnalyses the use of microorganisms for the production of natural molecules for use in foods, including microbial production of food flavours and carotenoids

Magnesium and magnesium alloys offer a wealth of valuable properties, making them of great interest for use across a wide range of fields. This has led to extensive research focused on understanding the properties of magnesium and how these can be controlled during processing. Fundamentals of magnesium alloy metallurgy presents an authoritative overview of all aspects of magnesium alloy metallurgy, including physical metallurgy, deformation, corrosion and applications.
Beginning with an introduction to the primary production of magnesium, the book goes on to discuss physical metallurgy of magnesium and thermodynamic properties of magnesium alloys. Further chapters focus on understanding precipitation processes of magnesium alloys, alloying behaviour of magnesium, and alloy design. The formation, corrosion and surface finishing of magnesium and its alloys are reviewed, before Fundamentals of magnesium alloy metallurgy concludes by exploring applications across a range of fields. Aerospace, automotive and other structural applications of magnesium are considered, followed by magnesium-based metal matrix composites and the use of magnesium in medical applications.
With its distinguished editors and international team of expert contributors, Fundamentals of magnesium alloy metallurgy is a comprehensive tool for all those involved in the production and application of magnesium and its alloys, including manufacturers, welders, heat-treatment and coating companies, engineers, metallurgists, researchers, designers and scientists working with these important materials.
Overviews all aspects of magnesium alloy metallurgyDiscusses physical metallurgy of magnesium and thermodynamic properties of magnesium alloysReviews the formation, corrosion and surface finishing of magnesium and its alloys

The conservation of metallic archaeological and historic artefacts is a major challenge whether they are ancient bronzes or relics of our more recent industrial past. Based on the work of Working Party 21 Corrosion of Archaeological and Historical Artefacts within the European Federation of Corrosion (EFC), this important book summarises key recent research on analytical techniques, understanding corrosion processes and preventing the corrosion of cultural heritage metallic artefacts.
After an introductory part on some of the key issues in this area, part two reviews the range of analytical techniques for measuring and analysing corrosion processes, including time resolved spectroelectrochemistry, voltammetry and laser induced breakdown spectroscopy. Part three reviews different types of corrosion processes for a range of artefacts, whilst part four discusses on-site monitoring techniques. The final part of the book summaries a range of conservation techniques and strategies to conserve cultural heritage metallic artefacts.
Corrosion and conservation of cultural heritage metallic artefacts is an important reference for all those involved in archaeology and conservation, including governments, museums as well as those undertaking research in archaeology and corrosion science.
Summarises key research on analytical techniques for measuring and analysing corrosion processesProvides detailed understanding of corrosion processes and corrosion preventionDiscusses on-site monitoring techniques