A primary objective in a first course in mechanics is to help develop a student's ability first to analyze problems in a simple and logical manner, and then to apply basic principles to their solutions. A strong conceptual understanding of these basic mechanics principles is essential for successfully solving mechanics problems. This edition of Vector Mechanics for Engineers will help instructors achieve these goals. Continuing in the spirit of its successful previous editions, this edition provides conceptually accurate and thorough coverage together with a significant refreshment of the exercise sets and online delivery of homework problems to your students. The 12th edition has new case studies and enhancements in the text and in Connect. The hallmark of the Beer-Johnston series has been the problem sets.This edition is no different. Over 650 of the homework problems in the text are new or revised. One of the characteristics of the approach used in this book is that mechanics of particles is clearly separated from the mechanics of rigid bodies. This approach makes it possible to consider simple practical applications at an early stage and to postpone the introduction of the more difficult concepts. Additionally, Connect has over 100 Free-Body Diagram Tool Problems and Process-Oriented Problems. McGraw-Hill's Connect, is also available. Connect is the only integrated learning system that empowers students by continuously adapting to deliver precisely what they need, when they need it, how they need it, so that class time is more effective. Connect allows the professor to assign homework, quizzes, and tests easily and automatically grades and records the scores of the student's work. Problems are randomized to prevent sharing of answers an may also have a "multi-step solution" which helps move the students' learning along if they experience difficulty.

The first of the two volumes is divided into three parts. Part One begins by introducing xenobiotics in the broad context of physiological metabolism, and continues with an overview of the processes of drug disposition and metabolism. It then goes on to summarize the macroscopic and microscopic locations of drug metabolism in animals and humans. This is followed by an introduction to the all-important issue of the consequences of drug and xenobiotic metabolism, providing an initial overview of pharmacokinetic, pharmacological and toxicological consequences. The last chapter examines drug metabolism in the context of drug research, with a focus on medicinal chemistry.
The second part is a major component of the book, corresponding to the role of oxidoreductases as major agents of metabolism. Cytochromes P450 receive particular attention, namely their multiplicity, structure, catalytic mechanisms, and the various reactions they catalyze, while other oxidoreductases are also presented, such as flavin monooxygenases, monoamine oxidases and other amine oxidases, aldehyde oxidase and xanthine dehydrogenase, peroxidases, and dehydrogenases-reductases. Each drug-metabolizing enzyme or enzyme family begins with an Enzyme Identity Card summarizing its nomenclature and biochemical essentials.
Part Three begins with a survey of the classification, properties and catalytic mechanism of the innumerable hydrolases known or suspected to play a role in xenobiotic metabolism. The focus then shifts to a systematic presentation of the various substrate classes, namely carboxylic esters, amides and peptides, lactams and lactones, esters of inorganic acids, alkene and arene epoxides, and some miscellaneous hydrolyzable moieties.
With a foreword by Prof Leslie Z. Benet, the world's best and best-known biopharmaceutical scientist

This handy reference compiles the latest data on the corrosion behavior of materials coming into contact with CO2 -- with 95% of the contents previously unpublished.
It is clearly structured according to material, and covers metals, non-metallic inorganic materials and plastics as well as including information about corrosion protection.
The result is a must-have for all engineers and scientists dealing with corrosion problems in CO2-containing environments.

When Sir Cyril Burt died in 1971, he was widely recognized as Britain's most eminent educational psychologist whose studies of gifted and delinquent children, contributions to the development of factor analysis, and research on the inheritance of intelligence brought widespread acclaim. Within five years of his death, however, he was publicly denounced as a fraud who had fabricated data to conclude that intelligence is genetically determined. Examiners of the published data found serious inconsistencies that raised questions about their authenticity; the case has divided the scientific community ever since. Were the charges justified, or was he a victim of critics fearful of validating such a politically unacceptable scientific theory? This is an up-to-date and unbiased analysis of one of the most notorious scandals in science, now more timely and widely discussed than ever with the publication of The Bell Curve, the best-selling polemic that raises arguments comparable to Burt's. The distinguished contributors examine the controversial areas of Burt's work and argue that his defenders have sometimes, but by no means always, been correct, and that his critics have often jumped to hasty conclusions. In their haste, however, these critics have missed crucial evidence that is not easily reconciled with Burt's total innocence, leaving the perception that both cases are seriously flawed. An introductory chapter lays the background to the case, followed by an examination of Burt's work that relates to the controversy. The book concludes with a chapter on Burt's character, other cases of apparent scientific fraud, and the impact of Burt's alleged fabrications. These findings have profound implications not only for the study of psychology, but for the wider issues relating to integrity in scientific research, and the impact of intelligence testing on social policy.

The book "Green Technologies for the Environment" brings together experts in the field of biotechnology, chemistry, chemical engineering, environmental engineering and toxicology from both academia and industry, to discuss green processes for the environment. The topics included finding replacements for crude oil to meet both our energy needs as well as the supply of chemicals for the production of essential products, advances in chemical processing, waste valorization, alternative solvents, and developments in homogeneous and heterogeneous catalysis as well as enzyme-based processes for chemical transformations. Advances in green chemistry concepts will further enhance the field through the design of new chemicals and solvents. In addition, obtaining a better understanding of the mechanistic pathways involved in various reactions is essential toward advances in the field. The goal of the work described in each of the chapters is to address the need for best practices for chemical processes and for the production of chemicals, while promoting sustainability.

Whispers from the depths is more than just the story of the building of the Kariba Dam in the mid-1950s. Built in just five years against overwhelming odds, the dam is a monument to engineering excellence. Shrouded in political undertones, the construction of the dam was vital for the hydro-electric power it would provide for Zambia’s burgeoning copper industry. Little thought, however, appears to have been given to the future of the human and animal populations who lived in the valley that would be inundated when the dam was completed. The question has to be asked: Was this awe-inspiring man-made creation achieved at too high a cost in terms of the human suffering and environmental devastation it caused? Central to the story of Kariba was the fate of the Tonga people who had for centuries lived in the Gwembe valley, due to be flooded when the sluice gates were finally closed to halt the flow of the mighty Zambezi River. Approximately 57 000 people were forced to move from their ancestral homes, abandoning family graves and spiritual sites to the depths of Kariba's water. They became a dispersed people who have never been able to reunite as a cohesive society, never again been able to live peacefully on the banks of the river which gave them life. Animals, too, perished in their thousands despite the gallant efforts of wildlife personnel who mounted a hastily planned rescue mission known as Operation Noah. Whispers from the depths gives a voice to the all but forgotten BaTonga. It celebrates their unique culture but deplores the price they paid for progress – a price from which they themselves derived no benefit whatsoever.

A powerful guide to why even the most well-intentioned innovations go haywire, and the surprising ways we can change course to create a more positive future, by two celebrated experts working at the intersection of design, technology, and learning at Stanford University’s acclaimed d.school.

In Assembling Tomorrow, authors Scott Doorley and Carissa Carter explore the intangible forces that prevent us from anticipating just how fantastically technology can get out of control, and what might be in store for us if we don’t start using new tools and tactics. Despite our best intentions, our most transformative innovations tend to have consequences we can’t always predict. From the effects of social media to the uncertainty of AI and the consequences of climate change, the outcomes of our creations ripple across our lives. Time and again, our seemingly ceaseless capacity to create rubs up against our limited capacity to understand our impact.

Assembling Tomorrow explores how to use readily accessible tools to both mend the mistakes of our past and shape our future for the better. We live in an era of “runaway design,” where innovations tangle with our lives in unpredictable ways. This book explores the off-­­kilter feelings of today and follows up with actionables to alter your perspective and help you find opportunities in these turbulent times.

Mixed throughout are histories of the future, short pieces of speculative fiction that imagine the future as if it has already happened and consider the past with a critical yet hopeful eye so that all of us—as designers of our own futures—can create a better world for generations to come.

"More than anything else technology creates our world. It creates our wealth, our economy, our very way of being," says W. Brian Arthur. Yet despite technology's irrefutable importance in our daily lives, until now its major questions have gone unanswered. Where do new technologies come from? What constitutes innovation, and how is it achieved? Does technology, like biological life, evolve? In this groundbreaking work, pioneering technology thinker and economist W. Brian Arthur answers these questions and more, setting forth a boldly original way of thinking about technology.
"The Nature of Technology "is an elegant and powerful theory of technology's origins and evolution. Achieving for the development of technology what Thomas Kuhn's "The Structure of Scientific Revolutions "did for scientific progress, Arthur explains how transformative new technologies arise and how innovation really works. Drawing on a wealth of examples, from historical inventions to the high-tech wonders of today, Arthur takes us on a mind-opening journey that will change the way we think about technology and how it structures our lives. "The Nature of Technology "is a classic for our times.

The result of a collaboration between a theoretician and an experimentalist, this book is devoted to the static properties of flexible polymers in solution. It presents the vast progress made by both theory and experiment in recent years. Despite the variety in the chemical composition and physical properties of long polymer chains, when in solution they show a universality in their behaviour. On the experimental side, the use of photon and neutron scattering has led to a better understanding, while the use of computer simulation has also produced interesting results. This work is the result of a collaboration between a theoretician and an experimentalist, who have both worked for many years on polymer solutions.

"Environmental Engineering: Fundamentals, Sustainability, Design "presents civil engineers with an introduction to chemistry and biology, through a mass and energy balance approach. ABET required topics of emerging importance, such as sustainable and global engineering are also covered. Problems, similar to those on the FE and PE exams, are integrated at the end of each chapter. Aligned with the National Academy of Engineering's focus on managing carbon and nitrogen, the 2nd edition now includes a section on advanced technologies to more effectively reclaim nitrogen and phosphorous. Additionally, readers have immediate access to web modules, which address a specific topic, such as water and wastewater treatment. These modules include media rich content such as animations, audio, video and interactive problem solving, as well as links to explorations. Civil engineers will gain a global perspective, developing into innovative leaders in sustainable development.

This book considers the theory of linear electrical circuits in steady regimes and transients as well as common problems of synthesis of linear electrical circuits, the theory of electrical linear circuits with distributed parameters and the calculation of nonlinear electrical and magnetic circuits. It has been prepared for undergraduate students, bachelors, masters and postgraduates at this important stage of developing techniques and technologies.

A full history of the Rolex Oyster Perpetual Submariner watch. The first ever book authorized by Rolex.

For the first time, Rolex has authorized a wide-ranging account and full history of the Rolex Oyster Perpetual Submariner watch, in the first of a series taking a deep dive into the watches of the iconic brand.

Oyster Perpetual Submariner: The Watch That Unlocked The Deep, written by author, editor, and watch expert Nick Foulkes, is published by global design authority, Wallpaper, which brings its sharp, cinematic eye to the project, creating new and original photography in collaboration with Rolex to run alongside testimonies from renowned witnesses to the Submariner's illustrious 70-year history, including marine biologist Sylvia Earle, photographer David Doubilet, and aquanaut Dr Joe MacInnis – further highlighting the role this iconic timepiece continues to play in the exploration and protection of the marine environment.

For courses in architecture and civil engineering. Reinforced Concrete: Mechanics and Design uses the theory of reinforced concrete design to teach students the basic scientific and artistic principles of civil engineering. The text takes a topic often introduced at the advanced level and makes it accessible to all audiences by building a foundation with core engineering concepts. The 7th Edition is up-to-date with the latest Building Code for Structural Concrete, giving students access to accurate information that can be applied outside of the classroom. Students are able to apply complicated engineering concepts to real world scenarios with in-text examples and practice problems in each chapter. With explanatory features throughout, the 7th Edition makes the reinforced concrete design a theory all engineers can learn from.

Includes coverage of iPhones 12, 11, X, SE, 8, 7, and 6! When you're looking for the most up-to-date information on your iPhone, look no further than this edition of iPhone For Seniors For Dummies. It's fully updated to cover iOS 14, the software released in Fall of 2020 that runs all iPhones dating back to the iPhone 6. It doesn't matter if you have a brand new iPhone 12 or are sticking with the iPhone you've had for a few years. This book will help you navigate your device. Written especially for iPhone owners who don't need to know every detail of how their phone works, iPhone For Seniors For Dummies sticks to clear, friendly, step-by-step information on the essentials you'll use every day. It covers the basics of messaging with friends and family, using your iPhone as a web browser, watching television shows or movies, and taking and sharing photos and videos. Get to know which iPhone you own Upgrade to iOS 14 Add contacts to your Favorites list Connect your iPhone to wifi Track your well-being with the Health app Fix common problems when they occur When you're ready to build your skills and become the go-to iPhone guru for your friends, iPhone For Seniors For Dummies offers the insight you need to increase your know-how.

Equip learners with the tools for success in a career as a plumber with this comprehensive and updated edition of our bestselling textbook, published in association with City & Guilds. The new edition will help learners to: - Study with confidence, covering all core content for the 6035, 9189 and 8202 specifications, as well as the 355 and 356 plumbing and heating T Level occupational specialisms. - Target learning with detailed qualification mapping grids. - Get to grips with technical content presented in accessible language. - Enhance their understanding of plumbing practice with clear and accurate illustrations and diagrams demonstrating the technical skills you need to master. - Practise maths and English in context, with embedded 'Improve your maths' and 'Improve your English' activities. - Test their knowledge with end-of-chapter practice questions, synoptic assessments and practical tasks. - Prepare for the workplace with up-to-date information on relevant key regulations and industry standards. - Keep their knowledge current, with clear coverage of major modern cold water, hot water, central heating, sanitation, rainwater systems and environmental technologies.

This new book contributes to the understanding of industrial production as our main engine of welfare. Industrial production plays a key role in human culture and the improvement in lives. Economic growth, competition and profit are important items in this mechanism. However, they are not really the main reasons why industrial production is so important. This book highlights industrial production as an engine of welfare, which is considered its main benefit. The book's objective is to improve the understanding of the fundamental mechanisms of industrial production. Consequently, this is not a book about design theories. It is a book dedicated to industrial engineering. Its focus is on the systemic nature of industrial engineering and the perspective is primarily the innovation process - where products and processes are designed and developed in order to make productive fulfilment of customer's needs possible. The book is considered a contribution to the philosophy of Industrial Engineering.

Nanoscience and nanotechnology have functioned as effective "buzzwords " for at least a decade due to the unique properties that materials possess on the nanometer scale. The interest in nanoscience and nanotechnology is so great and so widespread that these topics are even being introduced at the K-12 level in some school districts. Nanoscience and nanotechnology have already improved many applications and have the potential to continue to do so, making it important for all types of scientists to stay up-to-date on research related to nanomaterials. In the first section of this book, a variety of synthetic methods used to make or functionalize nanomaterials are presented with work related to mesoporous materials, semiconductor nanowires, graphene, and carbon nanotubes included. The second section of the book presents accounts of using nanotechnology and nanoscience in a variety of ways. Overall, this book presents a snapshot of research covering synthetic studies of nanomaterials to applications of nanomaterials.

Amateur repairers of clocks and watches grow in number every year as they discover the delights and challenges of the horological hobby. Often an initiate will begin with one of the classic books on the craft for the professionals, published by NAG Press. This time, however, this book is for amateurs.The author, Anthony Whiten, was bitten by the horological bug and communicated his enthusiasm to others with the result, as he says, that he was asked so many questions he had to write this book! If the reader does not have the right tools or they are too expensive to buy, the author describes how to make alterations out of simple and easily obtainable materials, or how to avoid the necessity for the tool at all. He also describes how to dismantle and assemble movements, what may go wrong with them and how to set faults right. He tells you how to oil the right parts and how to restore cases in all stages of decay. The book is illustrated with over 270 line drawings specially drawn to the author's specification. These range from step-by-step demonstrations of how to do things, to diagrams of movements identifying each part and its position in the movement - a great help at the 'gulp and shut the case' stage. Tony Whiten is not a professional, but many who are will find his comments both stimulating and inspirational. The amateur will find a sympathetic guide because the author has been through all the agonies of learning by hand experience. He hopes that this book will help others to avoid making some of his worst mistakes and encourage them to tackle bigger and better problems in the future.

A primary objective in a first course in mechanics is to help develop a student's ability first to analyze problems in a simple and logical manner and then to apply basic principles to their solutions. A strong conceptual understanding of these basic mechanics principles is essential for successfully solving mechanics problems. This edition of Vector Mechanics for Engineers will help instructors achieve these goals. Continuing in the spirit of its successful previous editions this edition provides conceptually accurate and thorough coverage together with a significant refreshment of the exercise sets and online delivery of homework problems to your students. The 12th edition has new case studies and enhancements in the text and in Connect. The hallmark of the Beer-Johnston series has been the problem sets.This edition is no different. Over 650 of the homework problems in the text are new or revised. One of the characteristics of the approach used in this book is that mechanics of particles is clearly separated from the mechanics of rigid bodies. This approach makes it possible to consider simple practical applications at an early stage and to postpone the introduction of the more difficult concepts. Additionally Connect has over 100 Free-Body Diagram Tool Problems and Process-Oriented Problems. McGraw-Hill's Connect is also available. Connect is the only integrated learning system that empowers students by continuously adapting to deliver precisely what they need when they need it how they need it so that class time is more effective. Connect allows the professor to assign homework quizzes and tests easily and automatically grades and records the scores of the student's work. Problems are randomized to prevent sharing of answers an may also have a "multi-step solution" which helps move the students' learning along if they experience difficulty.

Beverages derived from fruits and vegetables are a rich source of vitamin C, carotenoids, phenolics and polyphenolics as well as other bioactives. The bioactives in nutraceutical beverages may act synergistically with one another and their effect may be amplified through fortification, cultivating practices, or biotechnological means. This book discusses factors in the formulation, chemistry, nutrition, and health effects of nutraceutical beverages.

Energy, water, affordable healthcare and global warming are four major concerns resulting from resource depletion, record high oil prices, clean water shortages, high costs of pharmaceuticals, and changing climate conditions. Among many potential solutions, advance in membrane technology is one of the most direct, effective and feasible approaches to solve these sophisticated issues. This membrane book presents cutting-edge membrane research and development for water reuse and desalination, energy development including biofuels, CO2 capture, pharmaceutical purification and separation, and biomedical applications.

Chiral molecules are ubiquitous in nature. Thus, it is not surprising to come across this phenomenon in the world of flavor substances. This book provides an overview on the analytical procedures currently applied to analyze chiral flavor substances at trace levels. It demonstrates several examples for the application of these techniques to determine naturally occurring enantiomeric compositions of chiral key flavor compounds in various natural systems. In addition to the analytical aspects, the contributions focus on the sensory properties of enantiomers and enlarge our knowledge on the correlation between configurations and odor properties and intensities of chiral flavor compounds. The practical importance of the topic is reflected by a discussion of merits and limitations of chiral analysis for the authenticity control of food flavorings. In addition, examples for the use of enzymes and microorganisms to obtain enantiopure flavor substances and thus to meet legal requirements for "natural" labeling are presented. Finally, the book covers aspects recently getting more and more in the focus of flavor science: What are the physiological mechanisms underlying the perception of sensory properties and does chirality matter in that respect?