Liquid Chromatography: Fundamentals and Instrumentation, Third Edition offers a single source of authoritative information on all aspects of the practice of modern liquid chromatography. The book gives those working in academia and industry the opportunity to learn, refresh, and deepen their understanding of the field by covering basic and advanced theoretical concepts, recognition mechanisms, conventional and advanced instrumentation, method development, data analysis, and more. This third edition addresses new developments in the field with updated chapters from expert researchers. The book is a valuable reference for research scientists, teachers, university students, industry professionals in research and development, and quality control managers.

Stunning advances in digital technology have given us a new wave of disarmingly human-like AI systems. Chatbots like ChatGPT, Claude and Gemini put the knowledge of all the world’s experts at our fingertips, and can generate meaningful sentences, equations and computer code. The march of this new technology is set to upturn our economies, challenge our democracies, and refashion society in unpredictable ways. We can expect these AI systems to soon be making autonomous decisions on the user’s behalf, with transformative impact on everything we do. It is vital we understand how they work. Can AI systems ‘think’, ‘know’ and ‘understand’? Could they manipulate or deceive you, and if so, what might they make you do? Whose interests do they ultimately represent? And when will they be able to move beyond words and take actions for themselves in the real world?

To answer these questions, neuroscientist and AI researcher Christopher Summerfield explains how these strange new minds work. He charts the evolution of AI, from the earliest inklings about thinking machines in the seventeenth century to today’s gargantuan deep neural networks. The resulting book is the most accessible, up-to-date and authoritative exploration of this radical new technology. Ultimately, armed with an understanding of AI’s mysterious inner workings, we can begin to grapple with the existential question of our age: can we look forward to a technological utopia, or are we in the process of writing ourselves out of history?

'In a time when too many minds seem closed, this is a masterful analysis of what it takes to open them' Adam Grant, author of the bestselling Think Again 'Optimistic, illuminating and even inspiring' Guardian As the world is increasingly polarised, it feels impossible to change the mind of someone with a conflicting view. But this book shows that you could be one conversation away from changing someone's mind about something, maybe a lot of things. Self-delusion expert and psychology nerd David McRaney sets out to discover not just what it takes to influence others, but why we believe in the first place. Along the way he meets a former Westboro Baptist Church member who was deradicalised on Twitter, goes deep canvassing to see how quickly people will surrender their character-defining views, finds a 9/11 Truther who turns his back on it all, and reveals how, within a few years, half a country can go from opposing the 'gay agenda' to happily attending same-sex weddings. Distilling the latest research in psychology and neuroscience, How Minds Change reveals how beliefs take hold, not over hundreds of years, but in less than a generation, in less than a decade, and sometimes in an instant.

Theories of Emotion is a philosophical introduction to the most influential theories of emotion of the past 60 years in philosophy, psychology, and biology. This multi-disciplinary approach provides the reader with a one-stop shop for encountering the key debates and cutting-edge ideas in what is becoming a central focus of contemporary thought. An introductory chapter on definitions of emotion is followed by three main sections on the way emotions are expressed, subjectively experienced, and related to action and motivation. This accessible but probing approach integrates philosophical analysis with innovative research in psychology and cognitive science, contextualizing current debates in the history of ideas from Darwin to pragmatism. Each section is introduced by a detailed illustration of a foundational thinker's work on emotion (Charles Darwin, William James, and John Dewey, respectively), showing how their insights and discoveries have shaped current views and suggesting ways in which they might still enrich contemporary approaches.

Over the past twenty years, there's been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting 'probabilistic genotyping' to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience

Basic Life Science Methods: A Laboratory Manual for Students and Researchers presents forty of the most executed life science assays. The authors use a consistent structure to cover the preparation, execution and analysis of data from each method. Assays include estimation of cholesterol fractions, C-Reactive Protein, Genomic DNA isolation, Agarose Gel Electrophoresis, RT-PCR, DNA solution preparation, how to design primers, and enzyme-linked immunosorbent assay (ELISA). This book provides a complete reference containing step-by-step instructions on how to run life science assays. Laboratory staff can also benefit of the book as a training resource.