Somatic genome manipulation is required when a sexual crossing approach cannot be used in breeding or genetic treatment of an individual organism. Examples can include gene- or cell-therapy of a person to correct disease, genetic improvement of vegetatively propagated plants, and genetic replacement of cytoplasm without significantly modifying the nuclear genome. The advantage of somatic genome manipulation is maintenance of the general genotype while correcting one or more traits. Somatic genome manipulation is also an option for genetic improvement of sexually propagated plants in polyploidy breeding or in overcoming issues of sexual incompatibility. Recent novel technologies in somatic genome manipulation are developing quickly but much of this literature is fragmented and difficult or inconvenient to access. This book represents the first attempt to assemble updated reviews, detailed protocols, and their applications in all fields in which somatic genome manipulation has thrived. This is a truely one-of-a-kind work that brings together the most important and relevant advances in somatic genome manipulation in plants, algae, microorganisms, humans and animals, and demonstrates where the science interacts and where it diverges. The chapters are written by experts on the topic with ready-to-use protocols that were originally developed or adapted from the literature in their laboratories. We expect that this book will be useful for students, researchers, and teachers in both plant and animal research as a resource for the latest information on somatic genome manipulation and for its useful laboratory methods.

Packed with beautiful scenes showing butterflies of the world flitting among flowers. Simply brush water over the black and white designs to watch the butterflies burst into a rainbow of colours.

Recent advances in the study of bats have changed the way we understand this illusive group of mammals. This volume consist of 25 chapters and 57 authors from around the globe all writing on the most recent finding on the evolution, ecology and conservation of bats. The chapters in this book are not intended to be exhaustive literature reviews, but instead extended manuscripts that bring new and fresh perspectives. Many chapters consist of previously unpublished data and are repetitive of new insights and understanding in bat evolution, ecology and conservation. All chapters were peer-reviewed and revised by the authors. Many of the chapters are multi-authored to provide comprehensive and authoritative coverage of the topics.

The past, present and future of the world's most popular and beloved pet, from a leading evolutionary biologist and great cat lover. Jonathan B. Losos unravels the secrets of the cat using all the tools of modern technology, from GPS tracking (you’ll be amazed where they roam) and genomics (what is your so-called Siamese cat, really?) to forensic archaeology. He tells the story of the cat’s domestication (if you can call it that) and gives us a cat's-eye view of the world today. Along the way we also meet their wild cousins, whose behaviours are eerily similar to even the sweetest of house cats. Drawing on his own research and life in his multi-cat household, Losos deciphers complex science and history and explores how selection, both natural and artificial, over the millennia has shaped the contemporary cat. Yet the cat, ever a predator, still seems to have only one paw out of the wild, and readily reverts to its feral ways as it occupies new habitats around the world. Looking ahead, this charming and intelligent book suggests what the future may hold for the special bond between Felis catus and Homo sapiens.

'A funny and beautifully written welcome to the enigmatic, weird and wonderful world of wasps' DAVE GOULSON, author of SILENT EARTH There may be no insect with a worse reputation than the wasp, and none guarding so many undiscovered wonders. Where bees and ants have long been the darlings of the insect world, wasps are much older, cleverer and more diverse. They are the bee's evolutionary ancestors - flying 100 million years earlier - and today they are just as essential for the survival of our environment. A bee, ecologist Professor Seirian Sumner argues, is just a wasp that has forgotten how to hunt. For readers of Entangled Life, Other Minds and The Gospel of Eels, this is a book to upturn your expectations about one overlooked animal and the wider architecture of our natural world. With endless surprises, this book might teach you about the wasps that spend their entire lives sealed inside a fig, about stinging wasps, about parasitic wasps, about wasps that turn cockroaches into living zombies, about how wasps taught us to make paper. It offers up a maligned insect in all its diverse, unexpected splendour; as both predator and pollinator, the wasp is an essential pest controller worldwide. Inside their sophisticated social worlds is the best model we have for the earth's major evolutionary transitions. In their understudied biology are clues to progressing medicine, including a possible cure for cancer. The closer you look at these spurned, winged insects - both custodians and bouncers of our planet - the more you see. Their secrets have so far gone mostly untapped, but the potential of the wasp is endless.

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

How many fingers do you have? How many toes? This engaging book teaches beginning readers how to count the parts of their bodies. Engage students in reading as they develop their early childhood literacy skills. With TIME For Kids content, this full-color book is aligned to state and national standards, and introduces students to simple informational text features.