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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelles (English, German, Paperback, Softcover reprint of the original 1st ed. 1954)
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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelles (English, German, Paperback, Softcover reprint of the original 1st ed. 1954)
Series: Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 11
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The properties of proteins are determined not only by the sequence
of amino-acid residues in the polypeptide chains, but also by the
con- figuration of the chains-the way in which the chains are
coiled or folded. It is probable that denaturation, the loss of
some of the specific properties of a native protein, may in many
cases be the result simply of a change in configuration of the
polypeptide chains, without any change whatever in the sequence of
amino-acid residues. During the past few years great progress has
been made in the attack on the determination of the sequence of
amino-acid residues in the poly- peptide chains of proteins,
through the work of SANGER and his collabora- tors (Io9, IIO) and
of other investigators. There has also been significant progress in
the attack on the problem of the configuration of polypeptide
chains, largely through the application of the X-ray diffraction
technique.
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