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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 92 (Hardcover, Edition.)
Loot Price: R5,427
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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 92 (Hardcover, Edition.)
Series: Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products, 92
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Resin glycosides are part of a very extensive family of secondary
metabolites known as glycolipids or lipo-oligosaccharides and are
constituents of complex resins (glycoresins) (1) unique to the
morning glory family, Convolvulaceae (2). These active principles
are responsible for the drastic purgative action of all the
important Convolvulaceous species used in traditional medicine
throughout the world since ancient times. Several commercial
purgative crude drugs can be prepared from the roots of different
species of Mexican morning glories. Their incorporation as
therapeutic agents in Europe is an outstanding example of the
assimilation of botanical drugs from the Americas as substitutes
for traditional Old World remedies (3). Even though phytochemical
investigations on the constituents of these drugs were initiated
during the second half of the nineteenth century, the structure of
their active ingredients still remains poorly known for some
examples of these purgative roots. During the last two decades, the
higher resolution c- abilities of modern analytical isolation
techniques used in conjunction with pow- ful spectroscopic methods
have facilitated the elucidation of the active principles of these
relevant herbal products. This chapter describes the ethnobotanical
information associated with the p- gative morning glory species and
how traditional usages were instrumental in plant selection for
chemical studies. The advantages and limitations of available
analy- cal techniques for the isolation, puri?cation, and structure
characterization of the individual constituents of these complex
glycoconjugates are also discussed.
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