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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Organization in the Spinal Cord - The Anatomy and Physiology of Identified Neurones (Paperback, Softcover reprint of the original 1st ed. 1981)
Loot Price: R2,825
Discovery Miles 28 250
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Organization in the Spinal Cord - The Anatomy and Physiology of Identified Neurones (Paperback, Softcover reprint of the original 1st ed. 1981)
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The research described in this book arose, in large part, from a
sense of frustration. For a number of years I had been studying the
physiology of the spinocervical tract, a somatosensory pathway, in
the cat's spinal cord. But I did not know, precisely, where the
cells of origin of the tract were located and therefore did not
know what they looked like or whether there were any correlations
between structure and function. It was true that electrophysiolo
gical experiments had indicated their probable situation in the
dorsal horn, and anatomical work had described the morphology of
cells that were likely to give rise to the axons of the tract; but
this was not satisfactory. With the publication, by Stretton and
Kravitz in 1968, of the Procion Yellow ionophoretic method for
intracellular staining, a new tool became available for studying
the morphology of physiologically identified neurones. We used the
techniques and, although very pleased with the beautiful appearance
of the dendritic trees of neurones seen in the fluorescence
microscope, we were again frustrated, this time by the inability of
Procion Yellow to stain axons for any considerable length.
Therefore, P. K. Rose and P. J. Snow and I began to try to develop
a method that would stain the axon, together with its collaterals,
in addition to the soma and dendrites of an intracellularly re
corded neurone."
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