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NMR Spectroscopy of Biological Solids (Paperback)
Loot Price: R1,969
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NMR Spectroscopy of Biological Solids (Paperback)
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Over the past decade, a myriad of techniques have shown that
solid-state nuclear magnetic resonance (NMR) can be used in a broad
spectrum of applications with exceptionally impressive results.
Solid-state NMR results can yield high-resolution details on the
structure and function of many important biological solids,
including viruses, fibril-forming molecules, and molecules embedded
in the cell membrane. Filling a void in the current literature, NMR
Spectroscopy of Biological Solids examines all the recent
developments, implementation, and interpretation of solid-state NMR
experiments and the advantages of applying them to biological
systems. The book emphasizes how these techniques can be used to
realize the structure of non-crystalline systems of any size. It
explains how these isotropic and anisotropic couplings interactions
are used to determine atomic-level structures of biological
molecules in a non-soluble state and extrapolate the
three-dimensional structure of membrane proteins using magic-angle
spinning (MAS). The book also focuses on the use of
multidimensional solid-state NMR methods in the study of aligned
systems to provide basic information about the mechanisms of action
of a variety of biologically active molecules. Addressing
principles, methods, and applications, this book provides a
critical selection of solid-state NMR methods for solving a wide
range of practical problems that arise in both academic and
industrial research of biomolecules in the solid state. NMR
Spectroscopy of Biological Solids is a forward-thinking resource
for students and researchers in analytical chemistry,
bioengineering, material sciences, and structural genomics.
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