This volume comprehensively covers recent prrogress in breast
cancer research. In an effort to successfully treat breast cancer,
it is imperative to a) fully understand the disease with all its
heterogeneity, b) understand the factors that influence the
metastasis of breast cancer to distant organs making it lethal and
c) understand the underlying processes that lead to the phenomenon
of drug-resistance making the disease particularly incurable. The
book explores all of these issues, including the phenomenon of
epithelial-mesenchymal-transition, cancer stem cells as well as
microRNAs in an attempt to better understand the disease in
connection to its heterogeneity/metastasis/drug-resistance as well
as to propose novel signaling pathways for therapeutic
intervention. The profiling of tumors to molecularly classify
breast cancers is also investigated so that customized targeted
therapies can be developed.
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