Breast Cancer Metastasis and Drug Resistance - Challenges and Progress (Hardcover, 2nd ed. 2019)

Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Advances in Experimental Medicine and Biology, 1152
Release date:	August 2019
First published:	2019
Editors:	Aamir Ahmad
Dimensions:	235 x 155 x 27mm (L x W x T)
Format:	Hardcover
Pages:	427
Edition:	2nd ed. 2019
ISBN-13:	978-3-03-020300-9
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	3-03-020300-X
Barcode:	9783030203009

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