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Obstructive Airway Diseases - Role of Lipid Mediators (Paperback)
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Obstructive Airway Diseases - Role of Lipid Mediators (Paperback)
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Incidences of inflammatory airway diseases are on the rise across
the world. Existing therapeutic options are ineffective, unsafe,
and expensive, and severe cases are nonresponsive to conventional
therapy. Therefore, it is imperative that research be undertaken to
discover new treatment options. Obstructive Airway Diseases: Role
of Lipid Mediators discusses clinically successful and potential
lipid targets that can make a difference in treating some of the
most intractable disease states. Topics discussed include:
Obstructive airway diseases, etiology, pathophysiology, and
existing therapeutic options What constitutes a lipid and how it is
broken down to generate biologically active mediators The role of
enzymes in the process of lipid mediator synthesis The biology of
arachidonic acid, platelet-activating factor, and lysophosphatidic
acid and the role they play in airway inflammation Products of
arachidonic acid metabolism such as leukotrienes, prostaglandins,
epieicosatrienoic acid, and oxoeicosatetraenoic acid Proresolution
lipid mediators in inflammatory airway disease conditions The role
of sphingosine and ceramide in inflammatory airway disease Protein
kinases activated by lipid mediators and those that trigger the
generation of lipid messengers The combined input of a panel of
international authorities on lipid mediators makes this volume a
valuable resource for all those involved in researching, teaching,
and studying airway inflammation as well as those involved in drug
discovery research. Punit Srivastava maintains a blog with
additional information about the book and his work.
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