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Biomaterial Control of Therapeutic Stem Cells (Hardcover)
Loot Price: R5,897
Discovery Miles 58 970
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Biomaterial Control of Therapeutic Stem Cells (Hardcover)
Series: Biomaterials Science Series, Volume 4
Expected to ship within 12 - 17 working days
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Human pluripotent stem cells (hPSCs), which cover both human
embryonic stem cells (hESCs) and induced pluripotent stem cells
(iPSCs), show promise for drug discovery and regenerative medicine
applications. These stem cells cannot be cultured on conventional
tissue culture dishes but on biomaterials that have specific
interactions with the hPSCs. Differentiation is regulated by the
biological and physical cues conferred by the biomaterial. This
book provides a systematic treatment of these topics bridging the
gap between fundamental biomaterials research of stem cells and
their use in clinical trials. The author looks at hPSC culture on a
range of biomaterial substrates. Differentiation and control of
hESCs and iPSCs into cardiomyocytes, osteoblasts, neural lineages
and hepatocytes are covered. The author then considers their
translation into stem cell therapies and looks at clinical trials
across spinal cord injury, macular degeneration, bone disease and
myocardial infarction. Finally, a chapter on future directions
closes the book. By using this book, the reader will gain a robust
overview of current research and a clearer understanding of the
status of clinical trials for stem cell therapies.
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