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Voltammetric Methods in Brain Systems (Hardcover, 1995 ed.)
Loot Price: R4,383
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Voltammetric Methods in Brain Systems (Hardcover, 1995 ed.)
Series: Neuromethods, 27
Expected to ship within 12 - 17 working days
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Efforts to measure neurotransmitters and related s- cies in living
brain tissue by faradic electrochemistry began in earnest in the
early 1970s. During the ensuing years, s- eral monographs and
various symposia on the subject have appeared. The present volume
of Neuromethods, Voltammetric Methods in Brain Systems, can be
considered different from previous offerings in several respects.
The methodology of in vivo electrochemistry has now reached a
stable level of maturity. It is no longer necessary to convince
interested re- ers that the techniques can measure, with specified
degrees of reliability, certain neurotransmitters and metabolites
in the extracellular fluid space. Moreover, the basic approaches of
electroanalytical measurements are more widely appre- ated by
neuroscientists and one need not explain in tutorial fashion the
details of oxidative electrochemistry. Nevert- less, in keeping
with the nature of the Neurumethods series, this is a "how to"
volume and readers will find ample detail on the preparation of
electrodes, practical experimental details, and the interpretation
of results. But the emphasis is strongly on the application of
voltammetric methods. The first two chapters deal with fundamentals
inherent in employing in vivo electrochemical measures. The first -
ticle offers an authoritative account of our understanding of the
surface states of carbon and carbon fiber electrodes. It provides a
rationale for the various pretreatments that have allowed the
"tuning" of electrode properties to obtain sen- tivity and fast
response times.
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