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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Clinical Cellular Immunology - Molecular and Therapeutic Reviews (Paperback, Softcover reprint of the original 1st ed. 1982)
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Clinical Cellular Immunology - Molecular and Therapeutic Reviews (Paperback, Softcover reprint of the original 1st ed. 1982)
Series: Contemporary Immunology
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The initial impetus to create a work combining aspects of cel-
lular immunology with their clinical applications grew from the ed-
itors' discussions of the area's needs with many of the leaders in
the field over a period of time. From the nucleus of ideas that
emerged, we have here attempted to create a unified and inte-
grated coverage of the rapidly growing field of cellular immunology
research and to trace out-from what seems at times a genuine
plethora of important new findings-the many and often impor- tant
clinical implications. Because of this approach, the chapters of
Clinical Cellular Im- munology attempt to be more than critical
reviews of research and clinical data, going beyond analysis to
synthesize working hypotheses about the functional meaning of
cellular immunological phenomena and their likely clinical
significance. To accomplish this undertaking, the text begins first
with a consid- eration of the molecular aspects of antigen
recognition (Luderer and Harvey) and of the ensuing regulatory
program initiation (Fathman). Then, the functional subsets
oflymphocytes as they in- teract to produce and control the
developing immune response are explored in detail (Sigel et a1.),
followed by a unique analytical dis- section of the action of
immunosuppressive agents on the sundry inductive and regulatory
immunologic pathways (Sigel et al.). A majority of the data and
conclusions drawn by the authors in the previous chapters arise
from work on murine systems, al- though wherever appropriate, human
data has been introduced.
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