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Evolution-adjusted Tumor Pathophysiology: - The Novel Language of Tumor Biology (Hardcover, 2013 ed.)
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Evolution-adjusted Tumor Pathophysiology: - The Novel Language of Tumor Biology (Hardcover, 2013 ed.)
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Combined modularized therapies for metastatic cancer are pointing
to central problems of communication among 'systems participators'.
A communication theory explains 'social engineering', endogenously
induced or by implementing non-normative boundary conditions.
Evolution-adjusted tumor pathophysiology is borne by an evolution
theory, which contrasts narrative evolution histories. The tool of
rationalizations constituting the tumor's normativity
(inflammation, immune response etc.) represents the non-genomic
counterpart of the tumor genome and should be additionally assessed
during tumor staging. Evolution-adjusted tumor pathophysiology
allows implementing applied systems biology, a novel clinical and
pharmaceutical technology for bioengineering tumor response and
personalizing tumor therapy. Combined modularized therapy,
evolution-adjusted tumor pathophysiology, and 'universal'
biomarkers concertedly address genetically based tumor
heterogeneity.
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