Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma (Paperback, Softcover reprint of the original 1st ed. 1996)

The publication of the Vth International Symposium 1995 on "Mechanisms of Secondary Brain Damage" in Mauls/ltaly is a collection of focused reviews reaching from novel molecular- and cell biological findings to aspects of clinical management in head injury and cerebral ischemia. A specific purpose of these series of meetings introduced in 1984 is for an exchange on problems of mutual interest by international high ranking experts from the basic sciences and related clinical disciplines, such as intensive care medicine, neurology, or neurosurgery. The present volume covers three major areas: (a) Molecular and cell biological mechanisms including inflammation (b) Novel findings on mechanisms and treatment in cerebral ischemia (c) Secondary processes in head injury, regeneration and treatment Molecular-and cell biology is currently attracting attention towards activation of genomic processes associated with the demise of cells referred to as "programmed cell death" and "apoptosis" which, actually, might be distinguished from each other. Thus, the phenomenon of delayed neuronal death in selectively vulnerable brain areas following brief interruption of blood flow is scrutinized as to the contribution of the activation of suicide genes. The physiological role of such a response, among others, is removal of surplus neurons during ontogenesis of the brain. Yet, evidence is accumulating that similar mechanisms playa role in cerebral ischemia, probably also trauma, where nerve-and other cells demonstrate features of apoptosis. Observations on protection of neurons by administration of protein synthesis inhibitors in cerebral ischemia provide more direct support.

General

Imprint:	Springer-Verlag
Country of origin:	Austria
Series:	Acta Neurochirurgica Supplement, 66
Release date:	February 2012
First published:	1996
Editors:	Alexander Baethmann • Oliver S. Kempski • Nikolaus Plesnila • Frank Staub
Dimensions:	279 x 210 x 7mm (L x W x T)
Format:	Paperback
Pages:	124
Edition:	Softcover reprint of the original 1st ed. 1996
ISBN-13:	978-3-7091-9467-6
Categories:	Books > Medicine > Surgery > Neurosurgery Books > Medicine > Other branches of medicine > Anaesthetics > General Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Other branches of medicine > Accident & emergency medicine > Intensive care medicine Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Promotions
LSN:	3-7091-9467-9
Barcode:	9783709194676

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