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The GnRH Neuron and its Control (Hardcover)
Loot Price: R3,917
Discovery Miles 39 170
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The GnRH Neuron and its Control (Hardcover)
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The GnRH Neuron and its Control examines the developmental biology
of GnRH neurons including their birth in the nasal placode of the
early embryo, perinatal programming, and sexual differentiation, in
addition to the hypothalamic mechanisms that control GnRH neurons
in adulthood to generate pulsatile and surge modes of GnRH
secretion throughout the major life stages including aging. The
morphology, electrophysiology, signal transduction pathways,
transcriptional regulators, and genomics underlying function of the
adult GnRH neuron is discussed in detail, as is the
neuroendocrinology and cell biology governing the generation of
both modes of GnRH release. The book also reviews the
neurobiological mechanisms and circuitry responsible for the
modulation of the activity of GnRH neurons by season, stress,
nutrition, and metabolism, and covers the current and potential
therapeutic approaches to regulating GnRH secretion and action.
Filled with newly identified research and classical fundamental
knowledge to GnRH biology, it will provide students, researchers,
and practitioners with an in-depth understanding of reproductive
neuroendocrinology. This is the fifth volume in the Masterclass in
Neuroendocrinology Series, a co- publication between Wiley and the
INF (International Neuroendocrine Federation) that aims to
illustrate highest standards and encourage the use of the latest
technologies in basic and clinical research and hopes to provide
inspiration for further exploration into the exciting field of
neuroendocrinology.
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