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Ribonucleases (Paperback, 2011 ed.) Loot Price: R5,464
Discovery Miles 54 640
Ribonucleases (Paperback, 2011 ed.): Allen W. Nicholson

Ribonucleases (Paperback, 2011 ed.)

Allen W. Nicholson

Series: Nucleic Acids and Molecular Biology, 26

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Loot Price R5,464 Discovery Miles 54 640 | Repayment Terms: R512 pm x 12*

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Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5' or 3' ends, ribonucleases perform essential roles in gene expression and regulation, genome replication and maintenance, host defense, stress response, and viral strategies of infection. Ribonucleases have also served as highly informative models to understand virtually every aspect of biomolecular structure and function. The fifteen chapters in this volume are written by recognized researchers in the field, and provide in-depth analyses of the major ribonuclease families. Particular focus is given to the relation of ribonuclease structure and mechanism to biological function, as well as ribonuclease dysfunction in certain disease states. Other topics include the evolutionary genetics and functional diversification of ribonucleases, engineered ribonucleases as anti-cancer agents, the mechanisms of action of artificial ribonucleases, and ribonucleases as models to understand protein folding and stability. This volume should serve as an essential reference for a broad range of researchers and educators with interests in RNA metabolism, enzymology, and gene regulation.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Nucleic Acids and Molecular Biology, 26
Release date: November 2013
First published: 2011
Editors: Allen W. Nicholson
Dimensions: 235 x 155 x 22mm (L x W x T)
Format: Paperback
Pages: 406
Edition: 2011 ed.
ISBN-13: 978-3-642-27090-1
Categories: Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN: 3-642-27090-5
Barcode: 9783642270901

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