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Protein Folding, Misfolding, and Disease - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
Loot Price: R2,704
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Protein Folding, Misfolding, and Disease - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
Series: Methods in Molecular Biology, 752
Expected to ship within 10 - 15 working days
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Protein misfolding is a key feature of many disorders in humans,
given that over twenty proteins are known to misfold and cause
disease. In Protein Folding, Misfolding, and Disease: Methods and
Protocols, experts in the field present a collection of current
methods for studying the analysis of protein folding and
misfolding, featuring strategies for expressing and refolding
recombinant proteins which can then be utilized in subsequent
experiments. This detailed volume also covers methods for analyzing
the formation of amyloid, protocols for determining the size and
structure of native and misfolded proteins, as well as specific
examples of where misfolded proteins can be examined using state-of
-the-art technologies. Written in the highly successful Methods in
Molecular Biology (TM) series format, chapters contain
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and key tips on troubleshooting and avoiding
known pitfalls. Up to date and authoritative, Protein Folding,
Misfolding, and Disease: Methods and Protocols offers researchers
the tools necessary to move ahead in this vital field.
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