This work has broad applications in clinical medicine, ranging from
prevention and treatment of organ and bone marrow transplant
rejection, management of various autoimmune disorders (for example,
rheumatoid arthritis), skin disease and asthma. Whereas
traditionally only a small repertoire of immunosuppressive agents
was available for clinical use, recent discoveries have
significantly increased the number of approved agents, resulting in
numerous trials to further evaluate their potential. There is also
considerable interest in the potential of cell-based therapies
(particularly hematopoietic stem and dendritic cell therapy) of
allo- and autoimmunity. Important recent advances in the
immunotherapy of allergic diseases are also covered in this book.
This volume is intended both for practising physicians and surgeons
and for biomedical scientists at the graduate/postdoctoral levels,
and is designed to provide the theory behind these various
approaches to immunosuppression, and to provide state-of-the-art
reviews of current developments in each area.
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