Recently, important new findings in the polyamine field and a
variety of new experimental systems have revolutionized the study
of these ubiquitous cellular components, essential for normal
growth and development. In "Polyamines: Methods and Protocols,"
leading researchers contribute an extensive collection of
up-to-date laboratory techniques for the further pursuit of
polyamine study. The volume delves into vital subjects such as
neoplasia studies with animal models and human patients,
therapeutic roles for polyamine inhibitors and analogs, polyamine
metabolism and oxidative damage, polyamines as regulators of
critical ion channels, as well as polyamine transport systems and
polyamine-responsive genes. Written in the highly successful
"Methods in Molecular Biology " series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and expert notes on troubleshooting and
avoiding known pitfalls.
Comprehensive and cutting-edge, "Polyamines: Methods and
Protocols" provides a key resource for all scientists pursuing the
study of this dynamic and significant aspect of cellular
biology."
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