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For the Love of Enzymes - The Odyssey of a Biochemist (Paperback, New Ed)
Loot Price: R832
Discovery Miles 8 320
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For the Love of Enzymes - The Odyssey of a Biochemist (Paperback, New Ed)
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In 1645 the Japanese samurai Musashi Miamoto wrote A Book of Five
Rings, which described the attitudes necessary for individual
success. Though he was a swordsman, his book was not limited to
combat but addressed the much broader question of how to achieve
excellence in life through study, discipline, and planning. It is
still avidly read in Japan today. Arthur Kornberg's book is a
modern-day Book of Five Rings that replaces the medium of
swordsmanship with that of biochemistry, particularly enzymology.
As Kornberg describes his successive research problems, the
challenges they presented, and the ultimate accomplishments that
resulted, he provides us with a primer in the strategies needed to
do scientific work of great significance. Moreover, these
strategies are played out in the context of solving some of the
great biochemical problems of the twentieth century. The ability to
manipulate and alter DNA fired a revolution that forever changed
the nature of biology. Arthur Kornberg is a primary architect of
that revolution, arguably one of the two or three most important
biologists of this time. Prior to Kornberg, genetic information and
later DNA were imbued by biologists with an almost vitalistic aura.
Kornberg demonstrated that DNA is a molecule synthesized by
enzymes, like all other chemical constituents of the cell. More
important, he trained a school of scientists who focused on and
discovered many of the enzymatic activities that act on DNA. It is
these enzymes in particular that allow modern "genetic
engineering." For the Love of Enzymes does not describe a single
lucky or hard-won accomplishment. Rather, it is the story of thirty
years of decisive campaigns, nearly all of which led to insights of
major significance. In relating his story, Kornberg never avoids
the difficult question of "why": why he felt classical nutritional
studies had reached a plateau, why he turned to enzymology as a
discipline in which the important answers would be found, and why
he believes the study of enzymes will grow ever more important as
we face the new scientific frontier of brain function. This book
will challenge students of biology and chemistry at all levels who
want to do important work rather than simply follow popular trends.
It will also delight and inform readers who wish to understand how
"real" science is done, and to learn of the values that guide one
of our greatest researchers.
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