Non-Myeloablative Allogeneic Transplantation (Hardcover, 2002 ed.)

Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.

General

Imprint:	Springer
Country of origin:	Netherlands
Series:	Cancer Treatment and Research, 110
Release date:	February 2002
First published:	2002
Editors:	Asad Bashey • Edward D. Ball
Dimensions:	235 x 155 x 14mm (L x W x T)
Format:	Hardcover
Pages:	216
Edition:	2002 ed.
ISBN-13:	978-0-7923-7646-0
Categories:	Books > Medicine > Surgery > Surgical oncology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	0-7923-7646-3
Barcode:	9780792376460

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