Anticandidal Agents provides the latest information on candida drug
resistance and its remedial implications. In this compilation,
users will find a comprehensive view on overcoming resistance in
anticandidal drugs, along with information on novel molecules.
Candida albicans is an opportunistic pathogenic fungus responsible
for life threating invasive and nosocomial infections across the
globe. Candidiasis is a major cause of morbidity among
immunocompromised patients. Infections caused by non-albicans
candida like C. glabrata, C. parapsilosis, and C. tropicalis have
also imposed a serious threat in the last few decades. Current
treatment of candidiasis relies primarily on antifungal agents
broadly categorized as azoles, polyenes, echinocandins,
allylamines, and pyrimidines. Lately, antifungal resistance has
emerged to be an obstruction of current treatment regime. A number
of reasons are described in detail. Understanding the mechanisms of
resistance is crucial for developing strategies for overcoming the
hindrance in current therapeutics.
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