Inflammation, hypoxia, vascular endothelial growth factor (VEGF)
and chemical mediators play a critical role in pathological
angiogenesis, macular oedema and fibrosis in diabetes. Laser
photocoagulation is still the currently approved gold standard for
treatment of clinically significant macular oedema and
proliferative diabetic retinopathy with strong evidence from large,
multicentric, randomized controlled trials. Emerging treatments
focus on pharmacologic interventions alone or in combination for
improving prognosis. The body of evidence for pharmacologic
interventions is growing and becoming convincing. Specific
inclusion and exclusion criteria, head to head comparisons between
anti VEGF, corticosteroid and laser therapy alone and in
combination are still required for dispassionate scientific
analysis. Our understanding of the mediators is increasing and
novel intervention strategies may be introduced by proteomics.
Combined intervention strategies may become the gold standard in
near future. This book presents the current evidence and emerging
paradigms in pathological ocular angiogenesis and macular oedema in
diabetes. An exciting and enlightening book altogether.
General
Imprint: |
Lap Lambert Academic Publishing
|
Country of origin: |
United States |
Release date: |
July 2013 |
First published: |
July 2013 |
Authors: |
Bali Jatinder
• Bali Renu T.
|
Dimensions: |
229 x 152 x 4mm (L x W x T) |
Format: |
Paperback - Trade
|
Pages: |
68 |
ISBN-13: |
978-3-659-41966-9 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
General
|
LSN: |
3-659-41966-4 |
Barcode: |
9783659419669 |
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