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Development of the Vertebrate Retina (Paperback, Softcover reprint of the original 1st ed. 1989)
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Development of the Vertebrate Retina (Paperback, Softcover reprint of the original 1st ed. 1989)
Series: Perspectives in Vision Research
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The vertebrate retina has a form that is closely and clearly linked
to its func tion. Though its fundamental cellular architecture is
conserved across verte brates, the retinas of individual species
show variations that are also of clear and direct functional
utility. Its accessibility, readily identifiable neuronal types,
and specialized neuronal connectivity and morphology have made it a
model system for researchers interested in the general questions of
the genet ic, molecular, and developmental control of cell type and
shape. Thus, the questions asked of the retina span virtually every
domain of neuroscientific inquiry-molecular, genetic,
developmental, behavioral, and evolutionary. Nowhere have the
interactions of these levels of analysis been more apparent and
borne more fruit than in the last several years of study of the
develop ment of the vertebrate retina. Fields of investigation have
a natural evolution, rdoving through periods of initial excitement,
of framing of questions and controversy, to periods of synthesis
and restatement of questions. The study of the development of the
vertebrate retina appeared to us to have reached such a point of
synthesis. Descriptive questions of how neurons are generated and
deployed, and ques tions of mechanism about the factors that
control the retinal neuron's type and distribution and the
conformation of its processes have been posed, and in good part
answered. Moreover, the integration of cellular accounts of
development with genetic, molecular, and whole-eye and behavioral
accounts has begun."
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