|
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
|
Buy Now
Autophagy in Infection and Immunity (Hardcover, 2009 ed.)
Loot Price: R5,785
Discovery Miles 57 850
|
|
|
Autophagy in Infection and Immunity (Hardcover, 2009 ed.)
Series: Current Topics in Microbiology and Immunology, 335
Expected to ship within 10 - 15 working days
|
Autophagy is a fundamental biological process that enables cells to
autodigest their own cytosol during starvation and other forms of
stress. It has a growing spectrum of acknowledged roles in
immunity, aging, development, neurodegeneration, and cancer
biology. An immunological role of autophagy was first recognized
with the discovery of autophagy's ability to sanitize the cellular
interior by killing intracellular microbes. Since then, the
repertoire of autophagy's roles in immunity has been vastly
expanded to include a diverse but interconnected portfolio of
regulatory and effector functions. Autophagy is an effector of
Th1/Th2 polarization; it fuels MHC II presentation of cytosolic
(self and microbial) antigens; it shapes central tolerance; it
affects B and T cell homeostasis; it acts both as an effector and a
regulator of Toll-like receptor and other innate immunity receptor
signaling; and it may help ward off chronic inflammatory disease in
humans. With such a multitude of innate and adaptive immunity
functions, the study of autophagy in immunity is one of the most
rapidly growing fields of contemporary immunological research. This
book introduces the reader to the fundamentals of autophagy, guides
a novice and the well-informed reader alike through different
immunological aspects of autophagy as well as the countermeasures
used by highly adapted pathogens to fight autophagy, and provides
the expert with the latest, up-to-date information on the specifics
of the leading edge of autophagy research in infection and
immunity.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
