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Books > Medicine > Clinical & internal medicine > Haematology
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Renaissance Of Sickle Cell Disease Research In The Genome Era (Hardcover)
Loot Price: R5,527
Discovery Miles 55 270
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Renaissance Of Sickle Cell Disease Research In The Genome Era (Hardcover)
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The Human Genome Project has spawned a Renaissance of research
faced with the daunting expectation of personalized medicine for
individuals with sickle cell disease in the Genome Era. This book
offers a comprehensive and timeless account of emerging concepts in
clinical and basic science research, and community concerns of
health disparity to educate professionals, students and the general
public about meeting this challenging expectation. Contributions
from physicians, research scientists, scientific administrators and
community workers make Renaissance of Sickle Cell Disease Research
in the Genome Era unique among the catalogue of books on this
genetic disorder.Part 1 offers detailed review of the National
Heart Lung and Blood Institute's leadership role in funding sickle
cell research, as well as developing progressive research
initiatives and the predicted impact of the Human Genome Project.
Part 2 gives an account of several clinical research perspectives
based on the Cooperative Study of Sickle Cell Disease. These
include recommendations for newborn screening, pain management,
stroke, transfusion therapy and pediatric and adult healthcare.
Part 3 offers novel insights into basic science research progress
and the impact of the Human Genome Project on the direction of
hemoglobinopathy research, including hemoglobin switching, bone
marrow transplantation and gene therapy. Part 4 engages the reader
in a culture-based discussion of the stigma attached to sickle cell
disease in the African American community and the apprehensions
about genetic research in this community. It concludes with a
global perspective on sickle cell disease from African, European
and American experiences. For readers seeking a definitive account
of sickle cell disease appropriate for students, researchers and
community workers, this collaborative effort is an ideal textbook.
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