Experienced cancer researchers from pharmaceutical companies,
government laboratories, and academia comprehensively review and
describe the arduous process of cancer drug discovery and approval.
They focus on using preclinical in vivo and in vitro methods to
identify molecules of interest, detailing the targets and criteria
for success in each type of testing and defining the value of the
information obtained from the various tests. They also define each
stage of clinical testing, explain the criteria for success, and
outline the requirements for FDA approval. A companion volume by
the same editor (Cancer Therapeutics: Experimental and Clinical
Agents) reviews existing anticancer drugs and potential anticancer
therapies. These two volumes in the Cancer Drug Discovery and
Development series reveal how and why molecules become anticancer
drugs and thus offer a blueprint for the present and the future of
the field.
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