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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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Macrolides - Properties, Synthesis and Applications (Hardcover)
Loot Price: R2,957
Discovery Miles 29 570
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Macrolides - Properties, Synthesis and Applications (Hardcover)
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Macrolide antibiotics represent a class of natural macrocyclic
products, one of the most clinically important antibiotics.
Unfortunately, the production and development of new macrolide
antibiotics are not represented enough in the pharmaceutical
industry today. The intention of the book is therefore not only to
be a teaching tool for students and experts, but also to draw the
attention of the general public to this extremely useful, cheap and
relatively unharmful effective anti-macrobials, and potential
anti-malarials. The authors introduce the different classes of
macrolides and their derivatives, principles of their biological
activity, their structure and interactions with biological targets
as well as synthetic methods to produce new macrolide antibiotics
of similar or improved properties. Special emphasis was put on
conjugates of macrolides with nucleobases or nucleosides with
numerous applications; among them the most important remains the
attempt to overcome bacterial resistance.
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