Molecular Chaperones and Cell Signalling (Paperback)

This book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?

General

Imprint:	Cambridge UniversityPress
Country of origin:	United Kingdom
Release date:	March 2011
First published:	2011
Editors:	Brian Henderson • A.Graham Pockley
Dimensions:	229 x 152 x 20mm (L x W x T)
Format:	Paperback - Trade
Pages:	346
ISBN-13:	978-0-521-17747-4
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
LSN:	0-521-17747-2
Barcode:	9780521177474

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