A complete reference for fermentation engineers engaged in
commercial chemical and pharmaceutical production, "Fermentation
and Biochemical Engineering Handbook" emphasizes the operation,
development and design of manufacturing processes that use
fermentation, separation and purification techniques. Contributing
authors from companies such as Merck, Eli Lilly, Amgen and
Bristol-Myers Squibb highlight the practical aspects of the
processes-data collection, scale-up parameters, equipment
selection, troubleshooting, and more. They also provide relevant
perspectives for the different industry sectors utilizing
fermentation techniques, including chemical, pharmaceutical, food,
and biofuels.
New material in the third edition covers topics relevant to
modern recombinant cell fermentation, mammalian cell culture, and
biorefinery, ensuring that the book will remain applicable around
the globe. It uniquely demonstrates the relationships between the
synthetic processes for small molecules such as active ingredients,
drugs and chemicals, and the biotechnology of protein, vaccine,
hormone, and antibiotic production. This major revision also
includes new material on membrane pervaporation technologies for
biofuels and nanofiltration, and recent developments in
instrumentation such as optical-based dissolved oxygen probes,
capacitance-based culture viability probes, and in situ real-time
fermentation monitoring with wireless technology. It addresses
topical environmental considerations, including the use of new
(bio)technologies to treat and utilize waste streams and produce
renewable energy from wastewaters. Options for bioremediation are
also explained.
Fully updated to cover the latest advances in recombinant cell
fermentation, mammalian cell culture and biorefinery, along with
developments in instrumentation Industrial contributors from
leading global companies, including Merck, Eli Lilly, Amgen, and
Bristol-Myers SquibbCovers synthetic processes for both small and
large molecules
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