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Odontogenesis - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2012)
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Odontogenesis - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2012)
Series: Methods in Molecular Biology, 887
Expected to ship within 10 - 15 working days
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Only in recent times has the possibility of growing and implanting
replacement teeth, made from one's own cells, moved into the realm
of realistic possibilities; however, the molecular and cellular
mechanisms of tooth development must be studied in a range of
vertebrates, from zebrafish to mice, so that evolutionarily
conserved network kernels, which will define the cellular states of
generic vertebrate tooth development, can be recognized. In
Odontogenesis: Methods and Protocols, experts in the field examine
techniques to approach this burgeoning field. This detailed volume
includes chapters on the detection of "tooth development" gene
expression, both at the RNA and protein level, current approaches
to the manipulation of gene expression levels and subsequent
analysis of tooth phenotypes, as well as chapters concerning
current efforts to get living tooth implants working without
waiting for a full understanding of the developmental pathways at
the molecular level. Written in the highly successful Methods in
Molecular Biology (TM) series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips for troubleshooting and avoiding
known pitfalls. Practical and easy to use, Odontogenesis: Methods
and Protocols aims to help researchers move forward toward the
ultimate goal of getting a "bioengineered tooth" into the patient's
mouth.
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