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PET for Drug Development and Evaluation (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R4,256
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PET for Drug Development and Evaluation (Paperback, Softcover reprint of the original 1st ed. 1995)
Series: Developments in Nuclear Medicine, 26
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Can drug development and evaluation be improved by the use of
positron emission tomography (PET)? PET is now well established and
many PET centres participate in networks that warrant the quality
of their research. PET allows one to follow the effect of a drug on
a variety of patients' metabolic parameters. In addition, PET may
be used to follow the fate in vivo of a compound, allowing
visualisation of its binding to specific receptors and a direct
study of the mechanism of drug action in normal and pathological
situations. The book shows the fields in which PET offers new and
unique information for the development of drugs (conception,
toxicity, pharmacokinetics and metabolism, clinical research, and
relations between clinical and biological effects) and evaluates
fields in which PET may shorten the development time of drugs.
Audience: Professionals in the pharmaceutical industry in all areas
of drug discovery and pharmacology, pre-clinical testing,
pharmacokinetics and metabolism, clinical evaluation, registration
and regulatory affairs. Government health authority representatives
who assess data and documentation on new drug development and
radiopharmaceuticals. Academic experts concerned with any of these
areas.
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