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Some Current Concepts of Synaptic Organization (Paperback)
Loot Price: R2,942
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Some Current Concepts of Synaptic Organization (Paperback)
Series: Advances in Anatomy, Embryology and Cell Biology, 55/4
Expected to ship within 10 - 15 working days
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The accumulation of literature dealing with the structure and
function of synapses presents the synaptologist with a formidable
problem. The diverse interests now en- compassed by synaptology,
and the many facets of neurobiology mirrored in these interests,
make the task of reviewing synaptic organization a major one.
Selection must be made and, if the reader is not to be misled,
biases must be exposed. My frame of reference is the presynaptic
terminal, that is, the enlarged termination of the axon (Figs. 1
and 2). This includes the specialized presynaptic membrane run-
ning alongside the cleft region and associated with the dense
projections and presyn- tic vesicular grid (Figs. 1 and 8). Within
the cytoplasm of the terminal are the synaptic and coated vesicles,
mitochondria, the micromamentous presynaptic network and possibly
microtubules. My approach to the presynaptic terminal will rely
principally on mor- phological concepts, although biochemical
features of the composition of the ju- tional region are essential
for a basic understanding of synaptic organization and ref- erence
to these will also be made.
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