One of the most exciting areas of cancer research now is the
development of agents which can target signal transduction pathways
that are activated inappropriately in malignant cells. The
understanding of the molecular abnormalities which distinguish
malignant cells from their normal counterparts has grown
tremendously.
This volume summarizes the current research on the role that signal
transduction pathways play in the pathogenesis of cancer and how
this knowledge may be used to develop the next generation of more
effective and less toxic anticancer agents.
Series Editor comments:
"The biologic behavior of both normal and cancer cells is
determined by critical signal transduction pathways. This text
provides a comprehensive review of the field. Leading investigators
discuss key molecules that may prove to be important diagnostic
and/or therapeutic targets."
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