For this forth edition, the book has been updated thoroughly, with
particular emphasis on modulation of chromatin structure by histone
modifications/ remodelling complexes and the role of co-activators/
co-repressors. Methods used to analyse gene expression have also
been given more attention, with a new section added on methods for
examining DNA binding by transcription factors. Additionally, new
sections have been added on coupling of transcription factors.
Additionally, new sections have been added on coupling of
transcription with post-transcriptional process and negatively
acting sequence elements, which are of increasing prominence.
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