Molecular Genetics of Pancreatic Cancer (Hardcover, 2013 ed.)

Pancreatic cancer is a formidable disease, and advances in early detection and improved therapeutics have been slow to come forth. With new advances in molecular genetics in the field of pancreatic tumorigenesis, it is an opportune time to use these recent discoveries to enhance our understanding of pancreatic cancer biology and to improve outcomes in patients. In this volume, leading experts in the field shed light on these findings describing the mutational landscape of pancreatic cancer, including new inroads into our understanding of familial pancreatic cancer, epidemiology, the biology of K-ras signaling, and the emerging contribution of epigenetic alterations to disease initiation and progression. The distinctive pancreatic cancer-stroma ecosystem as determined by the dynamic interplay of inflammation, hallmark mutations, EMT, and cancer stem cells is described, and implications of these interactions in the context of development of novel, personalized therapeutic options are explored.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Release date:	April 2013
First published:	2013
Editors:	Diane M Simeone • Anirban Maitra
Dimensions:	235 x 155 x 18mm (L x W x T)
Format:	Hardcover
Pages:	235
Edition:	2013 ed.
ISBN-13:	978-1-4614-6548-5
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4614-6548-6
Barcode:	9781461465485

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