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Books > Social sciences > Sociology, social studies > Anthropology
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Risk Assessment of Prenatally-Induced Adverse Health Effects (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R3,106
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Risk Assessment of Prenatally-Induced Adverse Health Effects (Paperback, Softcover reprint of the original 1st ed. 1992)
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Since the thalidomide (Contergan) tragedy about 30 years ago the
induction of prenatally-induced morphological or functional defects
has been an area of extensive research. Risk assessment of
prenatally-induced adverse health effects is still a difficult task
from both experimental data as well asfrom observations in humans.
In the contributions to this book three major aspects are dealt
with: - Quantitative extrapolations of experimental data to the
situation possibly relevant for man. - The significance for a risk
assessment with respect to man of minor or rare structural
abnormalities observed in experimental studies - The future need to
assess congenital dysfunctions (e.g. of the hormone or the immune
system) beside the present evaulation of structural defects.
Limitations as well as gaps of the present knowledge in this area
of basic and applied research are pointed out. Since the results of
prenatally-induced lesions may manifest themselves not only pre-
but often not before late postnatally, numerous aspects of
structural and functional abnormaldevelopment must be studied in
experimental and clinical investigations.
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