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Multiple Origins of Sex Differences in Brain - Neuroendocrine Functions and their Pathologies (Paperback, Softcover reprint of the original 1st ed. 2013)
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Multiple Origins of Sex Differences in Brain - Neuroendocrine Functions and their Pathologies (Paperback, Softcover reprint of the original 1st ed. 2013)
Series: Research and Perspectives in Endocrine Interactions
Expected to ship within 10 - 15 working days
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In theoretical terms, sex differences in brains and behaviors of
laboratory animals offer the possibility of fascinating scientific
studies on a range of molecular phenomena such as genomic
imprinting, DNA methylation, chromatin protein modification,
non-coding DNA, potentially resulting in important neuroanatomical
and neurochemical sex differences in the brain. Such sex
differences could arise consequent to exposures to testosterone
early in development, or to other effects deriving from the Y
chromosome. However, this general subject has been treated with
much hyperbole. Historically, sex differences were assumed to be
present where they did not really exist, e.g. with respect to
mathematics, executive leadership, etc. etc. Under what
circumstances do we really care about sex differences in brain and
behavior? These circumstances concern human maladies whose
diagnoses are much different between boys and girls, or between
women and men. Prominent examples discussed in this volume include
autism, attention deficit hyperactivity disorders and congenital
adrenal hyperplasia. In fact, infant boys are more susceptible than
infant girls to a variety of disorders that arise early in
development. This volume then ends with a consideration of effects
of estrogenic hormones on the injured brain, and their roles as
protective agents.
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