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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes
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Diabetic Nephropathy - Strategy for Therapy (Paperback, Softcover reprint of the original 1st ed. 1986)
Loot Price: R1,464
Discovery Miles 14 640
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Diabetic Nephropathy - Strategy for Therapy (Paperback, Softcover reprint of the original 1st ed. 1986)
Series: Developments in Nephrology, 9
Expected to ship within 10 - 15 working days
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Diabetic nephropathy is a tragic illness. Its often insidious onset
in the insulin dependent (type I) diabetic, typically a young
adult, heralds the last act in the course of a disease that will
increasingly become the dominant preoccupation in the patient's
shortened life. For most type II diabetics, the beginning of
clinical renal insufficiency is but a phase in a continuous
deterioration that affects the integrity ofjob, marriage, and
family. The nephropathic diabetic is hypertensive, has worsening
retinopathy, and more often than not, is also plagued by peripheral
vascular insufficiency, heart disease, gastrointestinal
malfunction, and deepening depression. Until the 1980's, few type I
diabetics who became uremic (because ofdiabetic nephropathy) lived
for more than two years. Hardly any attained true rehabilitation.
This dismal prognosis is changing substantially for the better.
Research in diabetes has resulted in striking advances at both ends
of the type I diabetic's natural history. In one exciting clinical
trial now underway in London, Ontario, halfofchildhood diabetics
treated with cyclosporine within six weeks of onset
evince"permanent" disappearanceofhyperglycemia and the need for
insulin. At the otherendofthe natural historyofdiabetes for the
nephropathic patientwith worsening eye disease (renal-retinal
syndrome), who receives a kidney transplant, patient and graft
survival, two years after cadaveric kidney transplantation in type
I diabetics is now equal to that of the nondiabetic."
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