Handbook of Downstream Processing (Paperback, Softcover reprint of the original 1st ed. 1997)

The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of microorganisms, followed by the recovery and purification of the associated products. The engineers and biotechnologists who are involved in the full-scale process design of such facilities must be familiar with the variety of unit operations and equipment and the applicable regulatory requirements. This book describes current commercial practice and will be useful to those engineers working in this field in the design, construction and operation of pharmaceutical and biotechnology plants. It will be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces issues such as: Should the process be batch or continuous or a combination of batch and continuous? How should the optimum process design be developed? Should one employ a new revolutionary separation which could be potentially difficult to validate or use accepted technology which involves less risk? Should the process be run with ingredients formulated from water for injection, deionized water, or even filtered tap water? Should any of the separations be run in cold rooms or in glycol jacketed lines to minimize microbial growth where sterilization is not possible? Should the process equipment and lines be designed to be sterilized in-place, cleaned-in-place, or should every piece be broken down, cleaned and autoclaved after every turn?"

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	October 2011
First published:	1997
Authors:	E. Goldberg
Dimensions:	235 x 155 x 38mm (L x W x T)
Format:	Paperback
Pages:	720
Edition:	Softcover reprint of the original 1st ed. 1997
ISBN-13:	978-9401071987
Categories:	Books > Science & Mathematics > Chemistry > Organic chemistry > General Books > Professional & Technical > Biochemical engineering > Biotechnology > General Promotions
LSN:	9401071985
Barcode:	9789401071987

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