As the incidence of diabetes increases worldwide, the need for
recommendations on how to prevent and treat the condition grows
exponentially, and so does the need for an authoritative source for
information on the appropriate models to study the condition. The
new edition of Animal Models of Diabetes is that source. The book
presents updated and expanded information regarding the use of
models in experiments with both Type 1 and Type 2 diabetes.
The new edition compiles relevant time-saving information on
well-recognized models, including various mice, rats, minipigs, and
Rhesus monkeys, and provides extensive references for more in-depth
study. It contains new and updated referenced reviews on animals
with induced obesity as well as observations on retinopathy in
spontaneous diabetes resembling human lesions. The book discusses
nutritionally diabetes-prone animals and considerations of insulin
resistance and obesity. The contributors also address the
importance of recent findings on the pathogenesis of diabetes and
its complications in relation to human disease.
Including contributions from prominent experts in the field, the
book brings together scattered data and lucidly presents it. This
promotes the understanding of the etiopathology of diabetes and
offers a new grasp of the insulin action, its negative feedback
leading to insulin resistance, and its detrimental outcomes. The
book also includes new knowledge on specific complications of
diabetes, offering an incentive to test advanced modalities to
prevent and inhibit their occurrence.
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