This issue brings the rheumatologist on the current thinking on
treatment of Systemic Lupus Erythematosus, with an eye to the
future. Topics covered include B cell biology and related
therapies; glutamate receptor biology and its clinical significance
in neuropsychiatric SLE; platelet C4d and vascular complications;
biomarkers in lupus nephritis; endothelial function and its
implications for cardiovascular and renal disease in SLE; changing
worldwide epidemiology of SLE and its relationship to
environmental, ethnic, and other sociodemographic factors; work
loss, disability, quality of life, and compliance in SLE; pediatric
lupus; metabolic syndrome and related endocrine abnormalities; the
significance of interferon and the consequences of anti-interferon
in SLE; and cutaneous lupus and the CLASI instrument.
General
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