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DNA Microarrays - Current Applications (Hardcover, New)
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DNA Microarrays - Current Applications (Hardcover, New)
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DNA microarrays are the modern, parallel version of classic
molecular biology hybridization techniques allowing the exploration
of thousands of sequences in a single run. The technique permits
the complete analysis of genetic material and the monitoring of
expression changes occurring in a biological sample under various
conditions. Microarrays have been used successfully in various
research areas including: sequencing, single nucleotide
polymorphism (SNP) detection, characterization of protein-DNA
interactions, DNA computing, mRNA profiling, and many more.
Applications of microarrays in the biosciences include: gene
expression studies, disease diagnosis, pharmacogenomics, drug
screening, pathogen detection, and genotyping. This book focuses on
the current successful applications of microarrays in various areas
of bioscience. The authors describe the use of microarrays to
assist basic research and drug discovery by the generation of gene
expression maps, the reconstruction of gene networks and the study
of biochemical pathways, the classification of genes and biological
samples, and a real case study on the transcriptional effects of
vaccine treatment. An entire chapter is dedicated to applications
of microarrays that do not involve gene expression.
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