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Purine and Pyrimidine Metabolism in Man X (Hardcover, 2000 ed.)
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Purine and Pyrimidine Metabolism in Man X (Hardcover, 2000 ed.)
Series: Advances in Experimental Medicine and Biology, 486
Expected to ship within 10 - 15 working days
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th This volume contains articles presented at the X International
Symposium on Purines and Pyrimidines in Man, held on May 14 19,
2000 in Tel Aviv, Israel. The first symposium in this series took
place in Tel Aviv in 1973. Since then, the symposium has been held
every three years in different parts of the world, including
Europe, USA and Japan. The participants, in this series of
symposia, are characterised by a wide interest in the various
aspects of purines and pyrimidines in man, which include
biochemistry, genetics, pharmacology, physiology, clinics, etc.
Presentations in the symposia include clarification of metabolic
pathways, characterisation of enzyme structure and kinetics and
discoveries of new inborn errors of metabolism and suggestions for
new therapeutic approaches for these inborn errors. In addition,
development of new purine and pyrimidine derivatives for the
treatment of cancer and viral diseases, and many more subjects of
mutual interest were brought to the fore. With the development of
therapeutic means and of new research tools, we have witnessed
changes in the areas of interest. The interest in gout and uric
acid urolithiasis has lessened, whereas molecular aspects, the role
of purine and pyrimidine substances in neurotransmission and in
purinergic signaling appear to gain greater interest. The articles,
included in this volume, contain new data pertaining to the various
aspects detailed above.
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