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Methods for Investigating Localized Clustering of Disease (Paperback)
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Methods for Investigating Localized Clustering of Disease (Paperback)
Series: International Agency for Research on Cancer Scientific Publications, No.135
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Since the beginning of this century, "clusters" of certain forms of
cancer--particularly leukemia in children and Hodgkin's
disease--have been reported around locations of specific
environmental hazards. Identification of such clusters is not an
easy task, since there is no exact definition of what a cluster is.
This monograph describes the variety of statististical techniques
cuurently in use, and their application to simulated data-sets
chosen to represent a range of clustering scenarios. The scientists
who developed these techniques were invited to apply their
methodology to these data-sets and to share their conclusions in
this volume. In addition, these researchers describe in complete
detail how they proceeded with the analysis, since an element of
subjectivity figures prominently in the application and
interpretation of some of these methods. The identification and
analysis of disease clusters can yield significant clues in
epidemiologic research, and as such will continue to be an
important subject of cancer research and epidemiology for the
foreseeable future.
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