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Contemporary Topics in Molecular Immunology - Volume 9 (Paperback, Softcover reprint of the original 1st ed. 1983)
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Discovery Miles 15 430
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Contemporary Topics in Molecular Immunology - Volume 9 (Paperback, Softcover reprint of the original 1st ed. 1983)
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recipients and acceptance of allografts can be made. The authors
have the experi ence and ability to bridge the entire field of
transplantation and their article encompasses both clinical and
immunochemical data in this area. Their data show clearly that
matches for the DR antigens are more important than those at the
ABC loci in determination of graft survival. Additional relevant
factors, in cluding autoimmunity and other B-cell antigens, are
discussed and correlated with graft survival. The authors also
present pathology data concerning the distribution of HLA-DR
antigens in various tissues. These data indicate a fruitful area
for future investigations on the chemical aspects of the various
antigens encoded within the human MHC. Do changes in the structure
of lymphocyte surface glycoproteins, especially changes in their
carbohydrate portions, occur during normal lymphoid differen
tiation? Information about this question is limited, and pertinent
data are avail able for only a few proteins. Three of the proteins
are major glycoprotein con stituents of rodent thymocyte membranes:
the Thy- antigen, a glycosylated leukocyte sialoglycoprotein called
W3/13, and a high-molecular-weight glycopro tein known as the
leukocyte-common antigen. In his contribution, Pink thor oughly
characterizes these glycoproteins and discusses the evidence that
the structures change when a thymocyte differentiates into a
mature, peripheral T cell. A comparison is drawn between lymphocyte
glycoprotein changes and those that occur during red blood cell
differentiation. The reader will find Pink's discourse informative
and provocative. Mast cells, basophils, and related tumor lines
bind IgE with very high affinity."
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Release date: |
2013 |
First published: |
July 2013 |
Editors: |
F Inman
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Dimensions: |
229 x 152 x 14mm (L x W x T) |
Format: |
Paperback
|
Pages: |
245 |
Edition: |
Softcover reprint of the original 1st ed. 1983 |
ISBN-13: |
978-1-4684-4519-0 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Diseases & disorders >
Immunology >
General
|
LSN: |
1-4684-4519-7 |
Barcode: |
9781468445190 |
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